Reviewed, UniProtKB/Swiss-Prot Q0SP35 (KCY1_BORAP)

Names and origin

Protein names

Recommended name:
    Cytidylate kinase 1
      Short name=CK 1
    EC=2.7.4.14
Alternative name(s):
    Cytidine monophosphate kinase 1
      Short name=CMP kinase 1

Gene names

Name:	cmk1
Ordered Locus Names:	BAPKO_0130

Organism

Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP]

Taxonomic identifier

390236 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	221 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00238
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP cytidylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 221	221	Cytidylate kinase 1 HAMAP MF_00238		PRO_1000048188
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0SP35-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: A12685834C18A1BF	FASTA	221	25,513
	10 20 30 40 50 60 MIIAIDGPSA SGKSSIAREL SVKLGFKFIS SGYLYRIITL IAQRSFISGC DFISENRLLN 70 80 90 100 110 120 LVLENDISFN DSSFLLNGEN VENQILNDKI DFQVSFYSSY IGIRNIVNKK LREVVKFSDD 130 140 150 160 170 180 NYIIEGRDIT TIVFPESEFK IYLDASIKVR ALRRYKQRNG NETLEELERT LKIRDDVDKN 190 200 210 220 KQYGKLELSK GVFYLDTSYK GLDDVCNIII EKFNLKKVRE R

References

[1]

"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000395 Genomic DNA. Translation: ABH01393.1.
RefSeq	YP_709569.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SP35.
Genome annotation databases
GeneID	4227371.
GenomeReviews	Gene locus BAPKO_0130 in contig CP000395_GR.
KEGG	baf:BAPKO_0130.
NMPDR	fig|390236.5.peg.194.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0SP35.
OMA	GIRNIVN.
Enzyme and pathway databases
BioCyc	BAFZ390236:BAPKO_0130-MON.
Family and domain databases
HAMAP	MF_00238. [Tree]
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kin_d. [Graphical view]
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
ProDom	PD000657. Adenylate_kin. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00017. cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY1_BORAP

Accession

Primary (citable) accession number: Q0SP35

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)