Q0SP05 (Q0SP05_BORAP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Name:	alr EMBL ABH01423.1
Ordered Locus Names:	BafPKo_0157 EMBL AEL69390.1, BAPKO_0161 EMBL ABH01423.1

Organism

Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP] EMBL ABH01423.1

Taxonomic identifier

390236 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Spirochaetes › Spirochaetia › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group › Borrelia afzelii

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL ABQ43059.1
	Non-terminal residue	366	1	EMBL ABQ43059.1

Sequences

	Sequence		Length	Mass (Da)
	Q0SP05 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: DCD3E95D73B80FC3	FASTA	366	42,300
	10 20 30 40 50 60 MSSNKTIIIN LNNLEHNLNL IKNKIGEKEI VATLKGDAYG HGLINIFKFF KAKKINYFGL 70 80 90 100 110 120 SNIEDAKTLK KIDKSTKILM YIKVDKKEIK NLIKLELLPF VADFEYLFLI EKECALQKKK 130 140 150 160 170 180 IKVHLKIDVG MNRYGIKIDS ALEIATYIQN SKFLELEGVC SHLPTTENFK ITQKQIEQFL 190 200 210 220 230 240 FFLETLKQKN INPKFVHISN SGHIINYKLN PQFNMVRPGL ILYGYCPTLK NKKTTLNFKP 250 260 270 280 290 300 VLNLFSKVVF IKNVKKGEKI SYSGTFQAKE DMKIGIIPIG YFDGIPQNIN NNFYFLINNK 310 320 330 340 350 360 KCKIRGKVCM NLTIVEIPKD LKVETGSKVE IVSEKLSINE MSKFSKRSHY ELLCNIGKYE NRKYLD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Glockner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suhnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo.
[2]	"Comparative genome analysis: Selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M.B., Felder M., Suehnel J., Wilske B., Platzer M. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: PKo EMBL ABH01423.1.
[3]	"Wide Distribution of a High-Virulence Borrelia burgdorferi Clone in Europe and North America." Qiu W.G., Bruno J.F., McCaig W.D., Xu Y., Livey I., Schriefer M.M. Emerg. Infect. Dis. 14:1097-1104(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PKo EMBL ABQ43059.1.
[4]	"Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates." Casjens S.R., Mongodin E.F., Qiu W.G., Dunn J.J., Luft B.J., Fraser-Liggett C.M., Schutzer S.E. J. Bacteriol. 193:6995-6996(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo.
[5]	"Whole-Genome Sequences of Two Borrelia afzelii and Two Borrelia garinii Lyme Disease Agent Isolates." Casjens S.R., Mongodin E.F., Qiu W.-G., Dunn J.J., Luft B.J., Fraser-Liggett C.M., Schutzer S.E. J. Bacteriol. 193:6995-6996(2011) Cited for: NUCLEOTIDE SEQUENCE. Strain: PKo EMBL AEL69390.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000395 Genomic DNA. Translation: ABH01423.1. EF537505 Genomic DNA. Translation: ABQ43059.1. CP002933 Genomic DNA. Translation: AEL69390.1.
RefSeq	YP_005592380.1. NC_017238.1. YP_709599.1. NC_008277.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	390236.BAPKO_0161.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABH01423; ABH01423; BAPKO_0161. AEL69390; AEL69390; BafPKo_0157.
GeneID	12159112. 4227442.
KEGG	baf:BAPKO_0161. bafz:BafPKo_0157.
PATRIC	37188613. VBIBorAfz3878_0224.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0787.
HOGENOM	HOG000031444.
KO	K01775.
OMA	FKADKDM.
ProtClustDB	CLSK507396.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0SP05_BORAP

Accession

Primary (citable) accession number: Q0SP05

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)