ID   GLPK_BORAP              Reviewed;         501 AA.
AC   Q0SNS0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Glycerol kinase;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase;
DE   AltName: Full=Glycerokinase;
DE            Short=GK;
GN   Name=glpK; OrderedLocusNames=BAPKO_0250;
OS   Borrelia afzelii (strain PKo).
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia;
OC   Borrelia burgdorferi group.
OX   NCBI_TaxID=390236;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16914037; DOI=10.1186/1471-2164-7-211;
RA   Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M.,
RA   Suehnel J., Wilske B., Platzer M.;
RT   "Comparative genome analysis: selection pressure on the Borrelia vls
RT   cassettes is essential for infectivity.";
RL   BMC Genomics 7:211-211(2006).
CC   -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC       metabolism.
CC   -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC       phosphate.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; CP000395; ABH01508.1; -; Genomic_DNA.
DR   RefSeq; YP_709684.1; -.
DR   GeneID; 4227714; -.
DR   GenomeReviews; CP000395_GR; BAPKO_0250.
DR   KEGG; baf:BAPKO_0250; -.
DR   NMPDR; fig|390236.5.peg.302; -.
DR   HOGENOM; Q0SNS0; -.
DR   OMA; Q0SNS0; IAQREFT.
DR   BioCyc; BAFZ390236:BAPKO_0250-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00186; -; 1.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   PANTHER; PTHR10196:SF9; Glycerol_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    501       Glycerol kinase.
FT                                /FTId=PRO_1000020704.
FT   NP_BIND     409    413       ATP (By similarity).
FT   BINDING      11     11       Substrate (By similarity).
FT   BINDING      15     15       ATP (By similarity).
FT   BINDING      81     81       Substrate (By similarity).
FT   BINDING     133    133       Substrate (By similarity).
FT   BINDING     242    242       Substrate (By similarity).
FT   BINDING     264    264       ATP (By similarity).
FT   BINDING     307    307       ATP; via carbonyl oxygen (By similarity).
SQ   SEQUENCE   501 AA;  55691 MW;  199AC96FDE6C624C CRC64;
     MKYILSIDQG TTSSRAIVFD KNANIKGIAQ KEFTQIYPQP SWVEHDPTEI WGSQLGVITE
     ALANSRILPN EVDAIGITNQ RETTVIWEKN TGKPIYNAIV WQDRRTAKIC DQLTKEGKDK
     IILEKTGLVL DSYFSGTKIL WILDNVEGAR QKAENGELCF GTIDTWLLWN LTQKKVHATD
     YSNASRTLLL NIKTLEWDDE LLNILNIPKA ILPELKESST IYGKTDKSLF GAEIPIAGIA
     GDQFAATFGQ ACLKKGMAKN TYGTGCFLTV NIGKEPIINH ERLLTSIAWG RKKSVTYVLE
     GSVFIGGAVI QWLRDGLEFF RKSSDAESLA SSASDNGGVY FVPAFVGLGA PHWDSYARGT
     IIGITRGSTK AHITRAALES IAFQSFDILN TMKKSIPNFE IKELRVDGGA SQNNLLMQFQ
     ADLLECKVVR PKITETTALG AAYLAGLASG YWQSAEEIVS LWQVDKIFEP SMPKNQKEKL
     LENWNRAIER SKSWIQNSHS L
//