ID   IDI2_BORAP              Reviewed;         354 AA.
AC   Q0SMG9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Isopentenyl-diphosphate delta-isomerase;
DE            Short=IPP isomerase;
DE            EC=5.3.3.2;
DE   AltName: Full=Isopentenyl pyrophosphate isomerase;
GN   Name=fni; OrderedLocusNames=BAPKO_0728;
OS   Borrelia afzelii (strain PKo).
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia;
OC   Borrelia burgdorferi group.
OX   NCBI_TaxID=390236;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16914037; DOI=10.1186/1471-2164-7-211;
RA   Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M.,
RA   Suehnel J., Wilske B., Platzer M.;
RT   "Comparative genome analysis: selection pressure on the Borrelia vls
RT   cassettes is essential for infectivity.";
RL   BMC Genomics 7:211-211(2006).
CC   -!- FUNCTION: Catalyzes the 1,3-allylic rearrangement of the
CC       homoallylic substrate isopentenyl (IPP) to its allylic isomer,
CC       dimethylallyl diphosphate (DMAPP) (By similarity).
CC   -!- CATALYTIC ACTIVITY: Isopentenyl diphosphate = dimethylallyl
CC       diphosphate.
CC   -!- COFACTOR: FMN (By similarity).
CC   -!- COFACTOR: NADPH (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the IPP isomerase type 2 family.
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DR   EMBL; CP000395; ABH01959.1; -; Genomic_DNA.
DR   RefSeq; YP_710135.1; -.
DR   GeneID; 4227970; -.
DR   GenomeReviews; CP000395_GR; BAPKO_0728.
DR   KEGG; baf:BAPKO_0728; -.
DR   NMPDR; fig|390236.5.peg.742; -.
DR   HOGENOM; Q0SMG9; -.
DR   OMA; Q0SMG9; AMGVGSQ.
DR   BioCyc; BAFZ390236:BAPKO_0728-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0004452; F:isopentenyl-diphosphate delta-isomerase act...; IEA:HAMAP.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00354; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000262; FMN-dep_DH.
DR   InterPro; IPR011179; IPdP_isomerase.
DR   Gene3D; G3DSA:3.20.20.70; Aldolase_TIM; 1.
DR   PANTHER; PTHR10578:SF3; IPdP_isomerase; 1.
DR   Pfam; PF01070; FMN_dh; 1.
DR   PIRSF; PIRSF003314; IPP_isomerase; 1.
DR   TIGRFAMs; TIGR02151; IPP_isom_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Flavoprotein; FMN; Isomerase;
KW   Isoprene biosynthesis; NADP.
FT   CHAIN         1    354       Isopentenyl-diphosphate delta-isomerase.
FT                                /FTId=PRO_1000048435.
SQ   SEQUENCE   354 AA;  39148 MW;  093F76B2A945AE15 CRC64;
     MGIEPNILEN KKRHIDICLN KNDVKSGCNF LRFVKLKHNA LSDFNFSEID IKEEIFGYNI
     SMPVFISSMT GGGKEGNDFN KSLVKIANYL KIPIGLGSFK LLFKYPEYIR DFALKRYAHS
     IPLFANIGAV QIVEFGISRI VEMIKRLEVD AIIVHLNAGQ ELMNVNGDRN FKGIKESIAK
     LSNFISVPLI VKETGFGISP SDVKKLFQLG VSYIDLAGSG GTNWVLVEGM KGNNLNIASC
     FSDWGIPSIF TLLSINDSLK ANIFASGGYE TGMDIAKGIA LGAKLIGVAA VVLRAFYDSG
     EDAVFSLFSD YEHVLKMSMF LSGSKSLSDF RNNKYFLSSY LLAEFGVFKQ FYGT
//