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Q0SMC6

- G6PI_BORAP

UniProt

Q0SMC6 - G6PI_BORAP

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Borrelia afzelii (strain PKo)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei356 – 3561Proton donorUniRule annotation
Active sitei387 – 3871UniRule annotation
Active sitei502 – 5021UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:BAPKO_0774, BafPKo_0754
OrganismiBorrelia afzelii (strain PKo)
Taxonomic identifieri390236 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001825: Chromosome, UP000005216: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 530530Glucose-6-phosphate isomerasePRO_1000013943Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi390236.BAPKO_0774.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0SMC6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MINYKNLNEL ENFKILERID PEVLKTVLTG KRIKEYDITI EGDSVHYNYA
60 70 80 90 100
SKQINENHLK IFQNLSDEAN LIEKYKEILN GERVNISENR KVLHHLTRGQ
110 120 130 140 150
IGKDVIEDNK ENMREFFQSE LEKIYNFAKQ IHSGNIKSAN GKKFKNVVQI
160 170 180 190 200
GIGGSSLGPK ALYSSIKNYA KKHNLALMNG YFISNIDPDE SAEVLNSINI
210 220 230 240 250
DETLFIIVSK SGNTLETKAN MQFLINKLKS NGIKEYKKQM VIITLKNSML
260 270 280 290 300
ALEEKGYLEY FFMHDSIGGR FSPTSAVGLV LLALCFTEKI VKEILKGANK
310 320 330 340 350
ADKKSLNKNV KDNAPLLAAL ISIYERNVLN YSSNCIIAYS KAMENFYLHL
360 370 380 390 400
QQLEMESNGK SVNRFNETIN YKTVRIIWGG IGTDVQHSFF QMLHQGTDIV
410 420 430 440 450
PMDFIGFNET QLKEDVISDN SSSNDKLKAN LIAQIIAFSK GKENSNKNKN
460 470 480 490 500
FKGERPSALI YSKELTPYAI GSILSHYENK VMFEGFLLNI NSFDQEGVQL
510 520 530
GKTLANQILK NDTFEDEAIE SYSKKILKQD
Length:530
Mass (Da):60,223
Last modified:September 5, 2006 - v1
Checksum:i9CCFE79D9FDDED10
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH02002.1.
CP002933 Genomic DNA. Translation: AEL69947.1.
RefSeqiYP_005592937.1. NC_017238.1.
YP_710178.1. NC_008277.1.

Genome annotation databases

EnsemblBacteriaiABH02002; ABH02002; BAPKO_0774.
AEL69947; AEL69947; BafPKo_0754.
GeneIDi12158845.
4227073.
KEGGibaf:BAPKO_0774.
bafz:BafPKo_0754.
PATRICi37189805. VBIBorAfz3878_0787.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH02002.1 .
CP002933 Genomic DNA. Translation: AEL69947.1 .
RefSeqi YP_005592937.1. NC_017238.1.
YP_710178.1. NC_008277.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 390236.BAPKO_0774.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABH02002 ; ABH02002 ; BAPKO_0774 .
AEL69947 ; AEL69947 ; BafPKo_0754 .
GeneIDi 12158845.
4227073.
KEGGi baf:BAPKO_0774.
bafz:BafPKo_0754.
PATRICi 37189805. VBIBorAfz3878_0787.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity."
    Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M.
    BMC Genomics 7:211-211(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.
  2. "Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates."
    Casjens S.R., Mongodin E.F., Qiu W.G., Dunn J.J., Luft B.J., Fraser-Liggett C.M., Schutzer S.E.
    J. Bacteriol. 193:6995-6996(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.

Entry informationi

Entry nameiG6PI_BORAP
AccessioniPrimary (citable) accession number: Q0SMC6
Secondary accession number(s): G0IRI1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3