Q0SM86 (GCP_BORAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BAPKO_0817

Organism

Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP]

Taxonomic identifier

390236 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303288

Sequences

	Sequence		Length	Mass (Da)
	Q0SM86 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 7A646DED1E7EF6EB	FASTA	346	38,626
	10 20 30 40 50 60 MKVLGIETSC DDCCVAVVEN GIHILSNIKL SQKEHEKYYG VVPEIASRLH TEAIMSVCIK 70 80 90 100 110 120 ALKKANTKIS EIDLIAVTSR PGLIGSLIVG LNFAKGLAIS LKKPIICIDH ILGHLYAPLM 130 140 150 160 170 180 HSKIEYPFIS LLLSGGHTLI AKQKNFDDVE ILGRTLDDSC GEAFDKVAKH YDIGFPGGPN 190 200 210 220 230 240 IEQISKNGDE NTFKFPVTTF RKKENWYDFS YSGLKTACIH QLEKFKNKDN PTTKNNIAAS 250 260 270 280 290 300 FQKAAFENLI TPLKRAIKDT QIKKLVIAGG VASNLYLREK IDKLKIQTYY PPLDLCTDNG 310 320 330 340 AMIAGLGFNM YLKYGESPIE IEANSRIENY KNQYKRKNNE KNFSNA

References

[1]

"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000395 Genomic DNA. Translation: ABH02042.1.
RefSeq	YP_710218.1. NC_008277.1.
3D structure databases
ProteinModelPortal	Q0SM86.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SM86.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000003799; EBBORP00000003417; EBBORG00000003799.
GeneID	4227883.
GenomeReviews	Gene locus BAPKO_0817 in contig CP000395_GR.
KEGG	baf:BAPKO_0817.
NMPDR	fig|390236.5.peg.822.
PATRIC	37189887. VBIBorAfz3878_0825.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
GeneTree	EBGT00050000006822.
HOGENOM	HBG304663.
OMA	PAVGVHH.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BAFZ390236:BAPKO_0817-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BORAP

Accession

Primary (citable) accession number: Q0SM86

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program