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Q0SM65 (PTH_BORAP) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptidyl-tRNA hydrolase

Short name=PTH
EC=3.1.1.29
Gene names
Name:pth
Ordered Locus Names:BAPKO_0839
OrganismBorrelia afzelii (strain PKo) [Complete proteome] [HAMAP]
Taxonomic identifier390236 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083

Subunit structure

Monomer By similarity. HAMAP MF_00083

Subcellular location

Cytoplasm By similarity HAMAP MF_00083.

Sequence similarities

Belongs to the PTH family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 188188Peptidyl-tRNA hydrolase HAMAP MF_00083
PRO_0000264009

Sequences

Sequence LengthMass (Da)Tools
Q0SM65 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 00E472DCD36367BF

FASTA18821,334
        10         20         30         40         50         60 
MGLLILGLGN PGLEFSLTRH NVGFSLLDKI VSKNGLFLKR KKKYEYSELR VISRRVILVK 

        70         80         90        100        110        120 
PLTYMNLSGS LFPSIFSDFY MCIKNLLVVL DNVDLPLGKC RLKERGGMST HNGLKSISSV 

       130        140        150        160        170        180 
LGSSNYSRLY IGVGSNVMRD IKSFVLSRFC KDEIDRLEKL YDFLSDELID ISESNFKDKV 


QKINSSNF 

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References

[1]"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity."
Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M.
BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PKo.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000395 Genomic DNA. Translation: ABH02063.1.
RefSeqYP_710239.1. NC_008277.1.

3D structure databases

ProteinModelPortalQ0SM65.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0SM65.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000004073; EBBORP00000003691; EBBORG00000004073.
GeneID4227324.
GenomeReviewsGene locus BAPKO_0839 in contig CP000395_GR.
KEGGbaf:BAPKO_0839.
NMPDRfig|390236.5.peg.841.
PATRIC37189927. VBIBorAfz3878_0844.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0193.
GeneTreeEBGT00050000006854.
HOGENOMHBG610927.
OMAIKFKTGG.
ProtClustDBPRK05426.

Enzyme and pathway databases

BioCycBAFZ390236:BAPKO_0839-MONOMER.

Family and domain databases

HAMAPMF_00083. Pept_tRNA_hydro_bact.
[Tree]
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
Gene3DG3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KOK01056.
PANTHERPTHR17224. Pept_tRNA_hydro. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMSSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMsTIGR00447. Pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTH_BORAP
AccessionPrimary (citable) accession number: Q0SM65
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families