Q0SM32 (KCY2_BORAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytidylate kinase 2
Short name=CK 2
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase 2
Short name=CMP kinase 2

Gene names

Name:	cmk2
Ordered Locus Names:	BAPKO_0872

Organism

Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP]

Taxonomic identifier

390236 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP. HAMAP MF_00239
Subcellular location	Cytoplasm By similarity HAMAP MF_00239.
Sequence similarities	Belongs to the cytidylate kinase family. Type 2 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 178	178	Cytidylate kinase 2 HAMAP MF_00239		PRO_1000005666
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0SM32 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: D1EB06BF2D45ED42	FASTA	178	20,878
	10 20 30 40 50 60 MKIALSGKSG CGNTTVSSMI AKHYGLEFIN YTFHDIARER NIPFSEFYEK EIIGRDDYYW 70 80 90 100 110 120 DRYLDKRLFA LSKKNNTVLA SRLAIWISKS ADLKIYLYAK MEVRAERIMT REGGMYSDVL 130 140 150 160 170 SSTFNRDEND KKRYLAIYNI DIDDYSSETD LVIDVTNINS NEVFELIRDE IDKRNLKN

References

[1]

"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000395 Genomic DNA. Translation: ABH02096.1.
RefSeq	YP_710272.1. NC_008277.1.
3D structure databases
ProteinModelPortal	Q0SM32.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SM32.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000003832; EBBORP00000003450; EBBORG00000003832.
GeneID	4227149.
GenomeReviews	Gene locus BAPKO_0872 in contig CP000395_GR.
KEGG	baf:BAPKO_0872.
NMPDR	fig|390236.5.peg.874.
PATRIC	37189991. VBIBorAfz3878_0876.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1102.
GeneTree	EBGT00050000007179.
HOGENOM	HBG578180.
OMA	CAGFIFR.
ProtClustDB	PRK04182.
Enzyme and pathway databases
BioCyc	BAFZ390236:BAPKO_0872-MONOMER.
Family and domain databases
HAMAP	MF_00239. Cytidyl_kinase_type2. [Tree]
InterPro	IPR011892. Cyt_kin_arch. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR02173. Cyt_kin_arch. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY2_BORAP

Accession

Primary (citable) accession number: Q0SM32

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program