ID   ADEC_BORAP              Reviewed;         548 AA.
AC   Q0SLI9;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Adenine deaminase;
DE            Short=Adenase;
DE            Short=Adenine aminase;
DE            EC=3.5.4.2;
GN   Name=ade; OrderedLocusNames=BAPKO_3033;
OS   Borrelia afzelii (strain PKo).
OG   Plasmid lp34.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia;
OC   Borrelia burgdorferi group.
OX   NCBI_TaxID=390236;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16914037; DOI=10.1186/1471-2164-7-211;
RA   Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M.,
RA   Suehnel J., Wilske B., Platzer M.;
RT   "Comparative genome analysis: selection pressure on the Borrelia vls
RT   cassettes is essential for infectivity.";
RL   BMC Genomics 7:211-211(2006).
CC   -!- CATALYTIC ACTIVITY: Adenine + H(2)O = hypoxanthine + NH(3).
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- SIMILARITY: Belongs to the adenine deaminase family.
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DR   EMBL; CP000398; ABH02289.1; -; Genomic_DNA.
DR   RefSeq; YP_854306.1; -.
DR   GeneID; 4491154; -.
DR   GenomeReviews; CP000398_GR; BAPKO_3033.
DR   KEGG; baf:BAPKO_3033; -.
DR   NMPDR; fig|390236.5.peg.1051; -.
DR   HOGENOM; Q0SLI9; -.
DR   OMA; Q0SLI9; MYLMIRE.
DR   GO; GO:0000034; F:adenine deaminase activity; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006146; P:adenine catabolic process; IEA:InterPro.
DR   HAMAP; MF_01518; -; 1.
DR   InterPro; IPR006679; Adenine_deam.
DR   InterPro; IPR006680; Amidohydro_1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   TIGRFAMs; TIGR01178; ade; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Manganese; Plasmid.
FT   CHAIN         1    548       Adenine deaminase.
FT                                /FTId=PRO_0000296715.
SQ   SEQUENCE   548 AA;  61030 MW;  42FD591045226392 CRC64;
     MNLFKIKANY IDIFNKEIYP ASITIENGYI VSIEKIDATL DEYVLPGFID AHIHIESSFL
     IPSNFAHLVV QHGTVATISD PHEIANVNGI DGINFMINNS KKTEFKIFFG APSCVPALSS
     KFETSGHVLD DQDVDKLMES NDIYYLSEVM DFKGVINKDV EVINKINSAL KRNKVVDGHA
     PGLSPHLTLK YMSSGISTDH ECSTIEDARY KLSLGVKIII REGSAAKNFE SLHPLISECS
     NKYCDSLMFC FDDAHPNDIL HGHINSIVAR AIGYGHDFFD VLKIACINPV LHYKIPVGLL
     RIGDPADFII TKDIKTFKID KTYINGKLVY SDGISHIPLI SEIPINNFNC SEKSILDFKF
     STKNKMIPII NCINNQIITQ KTMIDSNLLA PDFQSNIAED ILKIAIINRY EDNSKISIGF
     IKNFGIRKGA IGSTVAHDSH NIIVVGTNDE YLCKATNIII ENKGGLCALN NEKTIIIKLP
     ISGLMSTLPA KEIAFQYMKL NDFCKNILGS QLDDPLMTLS FMSLTVVPHL KINDKGLFDV
     DSFCFLDY
//