Q0SLI9 (ADEC_BORAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase
Short name=Adenase
Short name=Adenine aminase
EC=3.5.4.2

Gene names

Name:	ade
Ordered Locus Names:	BAPKO_3033

Encoded on

Plasmid lp34

Organism

Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP]

Taxonomic identifier

390236 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 548	548	Adenine deaminase HAMAP MF_01518		PRO_0000296715

Sequences

	Sequence		Length	Mass (Da)
	Q0SLI9 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 42FD591045226392	FASTA	548	61,030
	10 20 30 40 50 60 MNLFKIKANY IDIFNKEIYP ASITIENGYI VSIEKIDATL DEYVLPGFID AHIHIESSFL 70 80 90 100 110 120 IPSNFAHLVV QHGTVATISD PHEIANVNGI DGINFMINNS KKTEFKIFFG APSCVPALSS 130 140 150 160 170 180 KFETSGHVLD DQDVDKLMES NDIYYLSEVM DFKGVINKDV EVINKINSAL KRNKVVDGHA 190 200 210 220 230 240 PGLSPHLTLK YMSSGISTDH ECSTIEDARY KLSLGVKIII REGSAAKNFE SLHPLISECS 250 260 270 280 290 300 NKYCDSLMFC FDDAHPNDIL HGHINSIVAR AIGYGHDFFD VLKIACINPV LHYKIPVGLL 310 320 330 340 350 360 RIGDPADFII TKDIKTFKID KTYINGKLVY SDGISHIPLI SEIPINNFNC SEKSILDFKF 370 380 390 400 410 420 STKNKMIPII NCINNQIITQ KTMIDSNLLA PDFQSNIAED ILKIAIINRY EDNSKISIGF 430 440 450 460 470 480 IKNFGIRKGA IGSTVAHDSH NIIVVGTNDE YLCKATNIII ENKGGLCALN NEKTIIIKLP 490 500 510 520 530 540 ISGLMSTLPA KEIAFQYMKL NDFCKNILGS QLDDPLMTLS FMSLTVVPHL KINDKGLFDV DSFCFLDY

References

[1]

"Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000398 Genomic DNA. Translation: ABH02289.1.
RefSeq	YP_854306.1. NC_008566.1.
3D structure databases
ProteinModelPortal	Q0SLI9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SLI9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000004778; EBBORP00000004353; EBBORG00000004778.
GeneID	4491154.
GenomeReviews	Gene locus BAPKO_3033 in contig CP000398_GR.
KEGG	baf:BAPKO_3033.
NMPDR	fig|390236.5.peg.1051.
PATRIC	37190378. VBIBorAfz3878_1068.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1001.
GeneTree	EBGT00050000006788.
HOGENOM	HBG725357.
OMA	MYLMIRE.
ProtClustDB	CLSK862557.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMs	TIGR01178. Ade. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC_BORAP

Accession

Primary (citable) accession number: Q0SLI9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program