Q0SJ33 (Q0SJ33_RHOSR) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 52.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Submitted name: Isocitrate dehydrogenase (NADP+) EMBL ABG92453.1 EC=1.1.1.42 EMBL ABG92453.1 | ||
| Gene names |
| ||
| Organism | Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG92453.1 | ||
| Taxonomic identifier | 101510 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus › ![]() |
Protein attributes
| Sequence length | 746 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Cofactor | Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3 |
Ontologies
| Keywords | |
|---|---|
| Ligand | Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3 |
| Molecular function | Oxidoreductase EMBL ABG92453.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro |
| Molecular_function | isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Region | 135 – 142 | 8 | Substrate binding By similarity PIRSR PIRSR009407-2 | ||||||
Sites | |||||||||
| Metal binding | 353 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 552 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Metal binding | 556 | 1 | Magnesium or manganese By similarity PIRSR PIRSR009407-3 | ||||||
| Binding site | 148 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Binding site | 551 | 1 | Substrate By similarity PIRSR PIRSR009407-2 | ||||||
| Site | 258 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
| Site | 423 | 1 | Critical for catalysis By similarity PIRSR PIRSR009407-1 | ||||||
Sequences
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References
| [1] | "The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. Eltis L.D.Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RHA1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000431 Genomic DNA. Translation: ABG92453.1. |
| RefSeq | YP_700611.1. NC_008268.1. |
3D structure databases | |
| ProteinModelPortal | Q0SJ33. |
| SMR | Q0SJ33. Positions 7-742. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 101510.RHA1_ro00618. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ABG92453; ABG92453; RHA1_ro00618. |
| GeneID | 4219534. |
| KEGG | rha:RHA1_ro00618. |
| PATRIC | 23200037. VBIRhoJos26306_0644. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG2838. |
| HOGENOM | HOG000240860. |
| KO | K00031. |
| OMA | PRTMGTV. |
| ProtClustDB | CLSK867411. |
Enzyme and pathway databases | |
| BioCyc | RJOS101510:GJJ1-618-MONOMER. |
Family and domain databases | |
| Gene3D | 3.40.718.10. 3 hits. |
| InterPro | IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view] |
| Pfam | PF03971. IDH. 1 hit. [Graphical view] |
| PIRSF | PIRSF009407. IDH_monmr. 1 hit. |
| TIGRFAMs | TIGR00178. monomer_idh. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | Q0SJ33_RHOSR | ||||||||
| Accession | Primary (citable) accession number: Q0SJ33 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
