Q0SHU0 (Q0SHU0_RHOSR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA-directed DNA polymerase III alpha subunit EMBL ABG92896.1
EC=2.7.7.7 EMBL ABG92896.1

Gene names

Name:	dnaE1 EMBL ABG92896.1
Ordered Locus Names:	RHA1_ro01069

Organism

Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG92896.1

Taxonomic identifier

101510 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	1178 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 EMBL ABG92896.1 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0SHU0 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 8198ACE426521759	FASTA	1,178	129,113
	10 20 30 40 50 60 MADSFVHLHN HTEYSMLDGA AKVGPLFEEA ERLGMSAVGM TDHGNMYGAS EFYNEAKKQG 70 80 90 100 110 120 IKPIIGIEAY IAPESRFNTK RVLWGDRSQK SDDVSGSGAY THMTMVAENA TGLRNLFKLS 130 140 150 160 170 180 SLASIEGQLG KWARMDEELI ATHHEGIIAT TGCPSGEIQT RLRLGHDREA LEAAAKWQEI 190 200 210 220 230 240 WGKDNFFLEL MDHGLSIERR VREGLLEISK KLEIPPLATN DCHYVTKEAA ENHEALLCIQ 250 260 270 280 290 300 TGKTLSDPTR FKFDGDGYYL KPAAEMRALW DDQVPGACDN TLLIAERVQS YDDVWAHHDR 310 320 330 340 350 360 MPIFPVPEGE TQGTWLRKEV MRGLDRRFPD GPPEEYLARA DYEIGVILEM GFPAYFLVVG 370 380 390 400 410 420 DLINHAREVG IRVGPGRGSA AGSLVAYAMG ITNIDPIPHG LLFERFLNPE RVSMPDIDID 430 440 450 460 470 480 FDDRRRGEMV RYATDKWGSD RVAQVITFGT IKTKAAIKDS ARVQFGQPGF AIADQITKAL 490 500 510 520 530 540 PPPIMAKDIS VSGITDPNHE RYKEAVEVRA LIDSNPDVAK IYQTAKGLEG LIRNAGVHAC 550 560 570 580 590 600 AVIMSSEPLM DAIPVWKRAQ DGAIITGWDY PSCEAIGLLK MDFLGLRNLT VIGDAIDNIK 610 620 630 640 650 660 ANRGIDLDLD TLALDDQATY ELLSRGDTLG VFQLDGSAMR DLLRRMQPTG FEDIVAVLAL 670 680 690 700 710 720 YRPGPMGMNA HNDYADRKNG RQEVKPIHPE LEEPLKEILA DTYGLIVYQE QIMQIAQKVA 730 740 750 760 770 780 GYSLGQADIL RRAMGKKKLS VLEEAYAGFR EGMLANEFSE PAIKALWDTI LPFAGYAFNK 790 800 810 820 830 840 SHAAGYGLVS FWTGYLKANY PAEYMAGLLT SVGDDKDKAA VYLADCRKMG ITVLPPDVNE 850 860 870 880 890 900 SEVNFASVGE DIRFGMGAVR NVGANVVGSI IKARKEKSKF VDFSDYLNKI DAAACSKKVT 910 920 930 940 950 960 ESLIKAGGFD SLGHPRKGLM LVHADAIDAV MGTKKAEAIG QFDLFGGDDA DESISSVFNV 970 980 990 1000 1010 1020 KIPDEEWDSK HRLALEREML GLYVSGHPLN GVEHVLSAQS DTAIPTILEG DIKDGTQVTV 1030 1040 1050 1060 1070 1080 GGILASVNRR INKNGLTWAS AQLEDLTGGI EVLFFPQAYS VYGMDVTEDS VVLVKARVSI 1090 1100 1110 1120 1130 1140 RDDRISLIAN DLAVPDLSAV GVAKPLAVSL PLRQCTKDKL GALRQVLTRH PGTSDVHVRL 1150 1160 1170 IGGTEVTLWK VDDVLRVEPS SALMGDLKAL LGPSCLSV

References

[1]

"The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. , Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R., Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W., Eltis L.D. Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed: 17030794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000431 Genomic DNA. Translation: ABG92896.1.
RefSeq	YP_701054.1. NC_008268.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SHU0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4219774.
GenomeReviews	Gene locus RHA1_ro01069 in contig CP000431_GR.
KEGG	rha:RHA1_ro01069.
PATRIC	23200945. VBIRhoJos26306_1092.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Enzyme and pathway databases
BioCyc	RSP101510:RHA1_RO01069-MONOMER.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0SHU0_RHOSR

Accession

Primary (citable) accession number: Q0SHU0

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)