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Q0SGN1 (SYR_RHOSR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:RHA1_ro01490
OrganismRhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP]
Taxonomic identifier101510 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018103

Regions

Motif130 – 14011"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q0SGN1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: DC3C0CEC0E8A2A2A

FASTA55059,199
        10         20         30         40         50         60 
MTPADLAELL RGTAAKVLDE RGLDVSVLPE TLTVERPRNP EHGDYATNVA MQVAKKVGTN 

        70         80         90        100        110        120 
PRELAGWLAE ALTAAEGIDS ADIAGPGFLN IRLAADAQGA IVAKILDEGA AFGSGHTLDG 

       130        140        150        160        170        180 
KRINLEFVSA NPTGPIHLGG TRWAAVGDAL GRILSTQGAA VTREYYFNDH GAQIDRFSRS 

       190        200        210        220        230        240 
LIAAAKGEPA PEDGYAGAYI ADIAAQVQSQ RPDVLELPAG EQQEVFRAIG VDLMFAHIKR 

       250        260        270        280        290        300 
TLHEFGVDFD VYFHENSLFE SGAVEKAVET LKDSGNLFQE DGAWWLKSTD FGDDKDRVVI 

       310        320        330        340        350        360 
KSDGNAAYIA GDIAYFQDKR SRGFDLCIYM LGADHHGYIG RLKAAAAAFG DDPDTVEVLI 

       370        380        390        400        410        420 
GQMVNLVRDG VAVKMSKRAG TVITLDDLVE AIGVDASRYA MIRSSVDSSI DIDLELWTST 

       430        440        450        460        470        480 
GNENPVYYVQ YAHARLSAIA RNAADLGIAV ADPDFSLLVS EQEGDLIRTL GEYPRVVTSA 

       490        500        510        520        530        540 
ANLREPHRIA RYLEELAGAY HRFYGACRIL PQGDEEVGPL HIARLALCDA SRQVLSNGLA 

       550 
LLGVSAPEQM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000431 Genomic DNA. Translation: ABG93305.1.
RefSeqYP_701463.1. NC_008268.1.

3D structure databases

ProteinModelPortalQ0SGN1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING101510.RHA1_ro01490.

Proteomic databases

PRIDEQ0SGN1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG93305; ABG93305; RHA1_ro01490.
GeneID4218868.
KEGGrha:RHA1_ro01490.
PATRIC23201803. VBIRhoJos26306_1509.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycRJOS101510:GJJ1-1489-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RHOSR
AccessionPrimary (citable) accession number: Q0SGN1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries