Q0SDL7 (Q0SDL7_RHOSR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Malate synthase G 2 HAMAP MF_00641
EC=2.3.3.9 HAMAP MF_00641

Gene names

Name:	glcB2 HAMAP MF_00641
Ordered Locus Names:	RHA1_ro02564

Organism

Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG94369.1

Taxonomic identifier

101510 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	739 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641 SAAS SAAS006253
Pathway	Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641 SAAS SAAS006253
Subunit structure	Monomer By similarity. HAMAP MF_00641 SAAS SAAS006253
Subcellular location	Cytoplasm By similarity HAMAP MF_00641.
Sequence similarities	Belongs to the malate synthase family. GlcB subfamily. HAMAP MF_00641

Ontologies

Keywords
Biological process	Glyoxylate bypass HAMAP MF_00641 SAAS SAAS006253 Tricarboxylic acid cycle SAAS SAAS006253 HAMAP MF_00641
Cellular component	Cytoplasm SAAS SAAS006253 HAMAP MF_00641
Molecular function	Acyltransferase EMBL ABG94369.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate cycle Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	352	1	Proton acceptor By similarity HAMAP MF_00641
	Active site	646	1	Proton donor By similarity HAMAP MF_00641

Sequences

	Sequence		Length	Mass (Da)
	Q0SDL7 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: BE2865C322228318	FASTA	739	79,977
	10 20 30 40 50 60 MEVCQVRKVS HFMTERVEVG GLQVAKVLYD FVNEEALPGT GVDADGFWSG AATVIDELAP 70 80 90 100 110 120 KNKALLSTRD DLQARIDGWH RDRAGTAIDP AEYKAFLTEI GYLVPEPAPF EVSTANVDTE 130 140 150 160 170 180 ITATAGPQLV VPVLNARFAL NASNARWGSL YDALYGTNAI PDDGGAEAGA TYNKVRGDRV 190 200 210 220 230 240 IAWARTFLDT AAPLAQGSHA DAARYTVDGT ALTVQLADGT VTGLAEPGKF VGYLGDPAAP 250 260 270 280 290 300 TSVLLRNHGL HAEIQIDPTS PIGSTDTAGV KDVVLESAVT TIMDFEDSVA AVDADDKVIG 310 320 330 340 350 360 YRNWLGLNRG DLTEEMTKGG TAFTRRLNPD RTYTAPDGSE LTLHGRSLLF VRNVGHLMTT 370 380 390 400 410 420 PAILHGDGTE IPEGILDALI TSLCAVHGLS TGEATGPLVN SRTGSIYIVK PKQHGPDEVA 430 440 450 460 470 480 FTTELFGRVE QVLGLPANTL KVGIMDEERR TTVNLAACIN EARERVVFIN TGFLDRTGDE 490 500 510 520 530 540 IHTSMEAGPM IRKAEMKKQT WITAYEDWNV DTGLACGLQG RAQIGKGMWA MTELMAEMLD 550 560 570 580 590 600 QKIGHPKAGA NTAWVPSPTG ATLHATHYHQ VDVVAVQNQL KGTRRATLDE ILTIPLAPST 610 620 630 640 650 660 DWSDAEKQEE LDNNCQSILG YVVRWIDAGV GCSKVPDIHD VALMEDRATL RISSQLLANW 670 680 690 700 710 720 IRHGVVTADQ VVQSLQRMAP IVDRQNQNDP TYRPLAPDFD TNIAFQAAKE LILDGTTQPS 730 GYTEPILHRR RREYKAANA

References

[1]

"The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. , Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R., Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W., Eltis L.D. Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed: 17030794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000431 Genomic DNA. Translation: ABG94369.1.
RefSeq	YP_702527.1. NC_008268.1.
3D structure databases
ProteinModelPortal	Q0SDL7.
SMR	Q0SDL7. Positions 14-739.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SDL7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4220116.
GenomeReviews	Gene locus RHA1_ro02564 in contig CP000431_GR.
KEGG	rha:RHA1_ro02564.
PATRIC	23203991. VBIRhoJos26306_2595.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2225.
HOGENOM	HBG350005.
OMA	PKMHGPD.
PhylomeDB	Q0SDL7.
ProtClustDB	PRK02999.
Enzyme and pathway databases
BioCyc	RSP101510:RHA1_RO02564-MONOMER.
Family and domain databases
HAMAP	MF_00641. Malate_synth_G. [Tree]
InterPro	IPR011076. Malate_synth-like. IPR023310. Malate_synth_G_beta_sub_dom. IPR001465. Malate_synthase. IPR006253. Malate_synthG. [Graphical view]
Gene3D	G3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KO	K01638.
PANTHER	PTHR21631:SF1. Malate_synthase. 1 hit.
Pfam	PF01274. Malate_synthase. 1 hit. [Graphical view]
SUPFAM	SSF51645. Malat_synth_like. 1 hit.
TIGRFAMs	TIGR01345. Malate_syn_G. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0SDL7_RHOSR

Accession

Primary (citable) accession number: Q0SDL7

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)