Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional repressor KstR2

Gene

kstR2

Organism
Rhodococcus jostii (strain RHA1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Controls the expression of a small regulon that may play a role in the utilization of cholesterol.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi36 – 5520H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciRJOS101510:GJJ1-4595-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional repressor KstR2
Gene namesi
Name:kstR2
Ordered Locus Names:RHA1_ro04598
OrganismiRhodococcus jostii (strain RHA1)
Taxonomic identifieri101510 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
Proteomesi
  • UP000008710 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204HTH-type transcriptional repressor KstR2PRO_0000405033Add
BLAST

Proteomic databases

PRIDEiQ0S7V2.

Interactioni

Subunit structurei

Homodimer.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRINGi101510.RHA1_ro04598.

Structurei

Secondary structure

1
204
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi12 – 3019Combined sources
Helixi37 – 437Combined sources
Helixi48 – 547Combined sources
Helixi58 – 8225Combined sources
Helixi87 – 10418Combined sources
Helixi106 – 1149Combined sources
Helixi117 – 1193Combined sources
Helixi123 – 1253Combined sources
Helixi126 – 14823Combined sources
Helixi158 – 16811Combined sources
Helixi171 – 1744Combined sources
Beta strandi180 – 1823Combined sources
Helixi184 – 19714Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IBDX-ray1.50A/B1-204[»]
ProteinModelPortaliQ0S7V2.
SMRiQ0S7V2. Positions 11-202.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ0S7V2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 7361HTH tetR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108RZE. Bacteria.
ENOG4111HHS. LUCA.
HOGENOMiHOG000249907.
OMAiANERFTY.
OrthoDBiPOG091H02BD.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0S7V2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPPADDTS GKSGRRTELL DIAATLFAER GLRATTVRDI ADAAGILSGS
60 70 80 90 100
LYHHFDSKES MVDEILRGFL DDLFGKYREI VASGLDSRAT LEALVTTSYE
110 120 130 140 150
AIDASHSAVA IYQDEVKHLV ANERFTYLSE LNTEFRELWM GVLEAGVKDG
160 170 180 190 200
SFRSDIDVEL AFRFLRDTAW VAVRWYRPGG SVTVDTVAKQ YLSIVLDGLA

SPHN
Length:204
Mass (Da):22,550
Last modified:September 5, 2006 - v1
Checksum:i6C9FD9985640EEFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000431 Genomic DNA. Translation: ABG96384.1.
RefSeqiWP_009477673.1. NC_008268.1.

Genome annotation databases

EnsemblBacteriaiABG96384; ABG96384; RHA1_ro04598.
GeneIDi4222149.
KEGGirha:RHA1_ro04598.
PATRICi23208105. VBIRhoJos26306_4637.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000431 Genomic DNA. Translation: ABG96384.1.
RefSeqiWP_009477673.1. NC_008268.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IBDX-ray1.50A/B1-204[»]
ProteinModelPortaliQ0S7V2.
SMRiQ0S7V2. Positions 11-202.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi101510.RHA1_ro04598.

Proteomic databases

PRIDEiQ0S7V2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG96384; ABG96384; RHA1_ro04598.
GeneIDi4222149.
KEGGirha:RHA1_ro04598.
PATRICi23208105. VBIRhoJos26306_4637.

Phylogenomic databases

eggNOGiENOG4108RZE. Bacteria.
ENOG4111HHS. LUCA.
HOGENOMiHOG000249907.
OMAiANERFTY.
OrthoDBiPOG091H02BD.

Enzyme and pathway databases

BioCyciRJOS101510:GJJ1-4595-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ0S7V2.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiKSTR2_RHOJR
AccessioniPrimary (citable) accession number: Q0S7V2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 8, 2011
Last sequence update: September 5, 2006
Last modified: September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.