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Q0S539 (G6PI1_RHOSR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase 1

Short name=GPI 1
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 1
Short name=PGI 1
Phosphohexose isomerase 1
Short name=PHI 1
Gene names
Name:pgi1
Ordered Locus Names:RHA1_ro05567
OrganismRhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP]
Taxonomic identifier101510 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus

Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 550550Glucose-6-phosphate isomerase 1 HAMAP-Rule MF_00473
PRO_0000252637

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5121 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0S539 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 20C5F1651E86995C

FASTA55060,028
        10         20         30         40         50         60 
MSSDITGTAA WQKLRDHHAQ IQSVHLRELF EKDPARGQEL TVTAGDLYID YSKHRIDRDT 

        70         80         90        100        110        120 
LGLLLELARS ADLEARRDAM FAGEHINTSE DRAVLHTALR LPADASLVVD GQDVVADVHE 

       130        140        150        160        170        180 
VLDRMGDFTD RVRSGEWRGA TGERIKTVVN IGIGGSDLGP VMVYRALRHY ADAGISVRFI 

       190        200        210        220        230        240 
SNVDPADLVR SLQGLDPATT LFIVASKTFS TLETLTNATA ARRWLLGGLG LGNEAVAKHF 

       250        260        270        280        290        300 
VAVSTHADRV AEFGIDTANM FGFWDWVGGR YSVDSAIGLS VMAAIGKERF AEFLAGFHAV 

       310        320        330        340        350        360 
DEHFRTAPLE ENAPVLLGLI GLWYSNFFGA ESRAVLPYSN DLVRFAAYLQ QLTMESNGKS 

       370        380        390        400        410        420 
VRADGTPVPT STGEIFWGEP GTNGQHAFYQ LLHQGTRLVP SDFIGFGEPT DDLPTADGTG 

       430        440        450        460        470        480 
SMHDLLMSNF FAQTKVLAFG KTAEEIAAEG TPEHLVPHKV MPGNRPSTTI LAPKLTPSVI 

       490        500        510        520        530        540 
GQLIALYEHQ VFVEGVVWGI DSFDQWGVEL GKTQAVELQP VLTAAEEPAA QSDSSTDSLV 

       550 
RWYRRQRGRA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000431 Genomic DNA. Translation: ABG97347.1.
RefSeqYP_705505.1. NC_008268.1.

3D structure databases

ProteinModelPortalQ0S539.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING101510.RHA1_ro05567.

Proteomic databases

PRIDEQ0S539.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG97347; ABG97347; RHA1_ro05567.
GeneID4223118.
KEGGrha:RHA1_ro05567.
PATRIC23210065. VBIRhoJos26306_5611.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMAMIALTHY.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycRJOS101510:GJJ1-5564-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI1_RHOSR
AccessionPrimary (citable) accession number: Q0S539
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways