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Protein

Glutamate decarboxylase

Gene

gadA

Organism
Rhodococcus jostii (strain RHA1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciRJOS101510:G1G71-5996-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadAImported
Ordered Locus Names:RHA1_ro06016Imported
OrganismiRhodococcus jostii (strain RHA1)Imported
Taxonomic identifieri101510 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
Proteomesi
  • UP000008710 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei278N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PRIDEiQ0S3U3

Interactioni

Protein-protein interaction databases

STRINGi101510.RHA1_ro06016

Structurei

3D structure databases

ProteinModelPortaliQ0S3U3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

Q0S3U3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKHHHHHRD VISPAYTGRL SIDPFPALRL PDEETDPEAA YRFIHDELML
60 70 80 90 100
DGSSRLNLAT FVTTWMDPEA DKLMAETFDK NMIDKDEYPA TAAIESRCVS
110 120 130 140 150
MVADLFHAPD LSTTDPASAT GVSTIGSSEA VMLGGLALKW LWRAKREAAG
160 170 180 190 200
KDTARPNLVL GSNVQVVWEK FCRYFDVEPK YLPMEKGRYV ITPEQVRDAV
210 220 230 240 250
DENTIGAVVI VGTTYTGELE PVAAIADALD ELAASGGPDV PIHVDAASGG
260 270 280 290 300
FVVPFLQPEL LWDFRVPRVA SINVSGHKYG LTYPGIGFVV WRDKEHLPEG
310 320 330 340 350
LVFRVNYLGG DMPTFTLNFS RPGNQVVGQY YNFLRLGRAG YRSIMQTLRD
360 370 380 390 400
TAVRVGKRIA EIEGFTLITD GTDIPVVAFE LVGDPGFTVF DVSHELRARG
410 420 430 440 450
WQVPAYTMPA DAEDVAVLRI VVREGFSADL GSLVAEAIEE VCAELREKGG
460
GRSTEQHFAH
Length:460
Mass (Da):50,627
Last modified:September 5, 2006 - v1
Checksum:i65A168B0681CF22F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000431 Genomic DNA Translation: ABG97793.1
RefSeqiWP_011598067.1, NC_008268.1

Genome annotation databases

EnsemblBacteriaiABG97793; ABG97793; RHA1_ro06016
GeneIDi4223567
KEGGirha:RHA1_ro06016
PATRICifig|101510.16.peg.6065

Similar proteinsi

Entry informationi

Entry nameiQ0S3U3_RHOJR
AccessioniPrimary (citable) accession number: Q0S3U3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health