Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0S3C9

- Q0S3C9_RHOSR

UniProt

Q0S3C9 - Q0S3C9_RHOSR

Protein

Alanine racemase

Gene

alr

Organism
Rhodococcus sp. (strain RHA1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei58 – 581Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei156 – 1561SubstrateUniRule annotation
    Active sitei287 – 2871Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei335 – 3351Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRJOS101510:GJJ1-6177-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:RHA1_ro06180Imported
    OrganismiRhodococcus sp. (strain RHA1)Imported
    Taxonomic identifieri101510 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
    ProteomesiUP000008710: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei58 – 581N6-(pyridoxal phosphate)lysineUniRule annotation

    Proteomic databases

    PRIDEiQ0S3C9.

    Interactioni

    Protein-protein interaction databases

    STRINGi101510.RHA1_ro06180.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0S3C9.
    SMRiQ0S3C9. Positions 28-394.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiIYSHLAL.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0S3C9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLAEAVPAD DHGHSEPAAP TQAPAPQAEA VVDLDAIAHN VRILRDSARD    50
    AAMMAVVKAD GYNHGAVPVA RAALAAGASE LGVTTVSEAL TLRRAGIDAP 100
    VLAWLHTVDA DFAPAIAAGV ELGVSSPRHL AAVVAAARSV GTTAIVTIKV 150
    DTGLNRNGVA PDELAQVLVD LARAQAEGSV RLRGIFSHLA HADEPHHAWI 200
    DSQRDRLISA IADAKRQGLV PEVVHLSNSA ATLTRPDLRF DMVRPGIAIY 250
    GLSPVPELGQ FGLRPAMTLR SRVALVKKVA AGEGVSYGHQ WVAPRDTTVA 300
    LLPFGYADGL PRSLSGRFEV QLGAQRRPGI GRVCMDQVVV DLGPDGGGVR 350
    EGDTAVFFGN GDLGEPNAQA WADELDTIHY EVVTGVRGRT VRSYVGGTGT 400
    Length:400
    Mass (Da):41,776
    Last modified:September 5, 2006 - v1
    Checksum:i6DD3A7C46876A760
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000431 Genomic DNA. Translation: ABG97957.1.
    RefSeqiYP_706115.1. NC_008268.1.

    Genome annotation databases

    EnsemblBacteriaiABG97957; ABG97957; RHA1_ro06180.
    GeneIDi4223731.
    KEGGirha:RHA1_ro06180.
    PATRICi23211301. VBIRhoJos26306_6226.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000431 Genomic DNA. Translation: ABG97957.1 .
    RefSeqi YP_706115.1. NC_008268.1.

    3D structure databases

    ProteinModelPortali Q0S3C9.
    SMRi Q0S3C9. Positions 28-394.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 101510.RHA1_ro06180.

    Proteomic databases

    PRIDEi Q0S3C9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG97957 ; ABG97957 ; RHA1_ro06180 .
    GeneIDi 4223731.
    KEGGi rha:RHA1_ro06180.
    PATRICi 23211301. VBIRhoJos26306_6226.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi IYSHLAL.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci RJOS101510:GJJ1-6177-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RHA1Imported.

    Entry informationi

    Entry nameiQ0S3C9_RHOSR
    AccessioniPrimary (citable) accession number: Q0S3C9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3