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Q0S3C9 (Q0S3C9_RHOSR) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201
EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
Name:alr EMBL ABG97957.1
Ordered Locus Names:RHA1_ro06180 EMBL ABG97957.1
OrganismRhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG97957.1
Taxonomic identifier101510 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus ›

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS000821

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site581Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2871Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1561Substrate By similarity HAMAP-Rule MF_01201
Binding site3351Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue581N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q0S3C9 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 6DD3A7C46876A760

FASTA40041,776
        10         20         30         40         50         60 
MTLAEAVPAD DHGHSEPAAP TQAPAPQAEA VVDLDAIAHN VRILRDSARD AAMMAVVKAD 

        70         80         90        100        110        120 
GYNHGAVPVA RAALAAGASE LGVTTVSEAL TLRRAGIDAP VLAWLHTVDA DFAPAIAAGV 

       130        140        150        160        170        180 
ELGVSSPRHL AAVVAAARSV GTTAIVTIKV DTGLNRNGVA PDELAQVLVD LARAQAEGSV 

       190        200        210        220        230        240 
RLRGIFSHLA HADEPHHAWI DSQRDRLISA IADAKRQGLV PEVVHLSNSA ATLTRPDLRF 

       250        260        270        280        290        300 
DMVRPGIAIY GLSPVPELGQ FGLRPAMTLR SRVALVKKVA AGEGVSYGHQ WVAPRDTTVA 

       310        320        330        340        350        360 
LLPFGYADGL PRSLSGRFEV QLGAQRRPGI GRVCMDQVVV DLGPDGGGVR EGDTAVFFGN 

       370        380        390        400 
GDLGEPNAQA WADELDTIHY EVVTGVRGRT VRSYVGGTGT

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000431 Genomic DNA. Translation: ABG97957.1.
RefSeqYP_706115.1. NC_008268.1.

3D structure databases

ProteinModelPortalQ0S3C9.
SMRQ0S3C9. Positions 28-394.
ModBaseSearch...

Protein-protein interaction databases

STRING101510.RHA1_ro06180.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG97957; ABG97957; RHA1_ro06180.
GeneID4223731.
KEGGrha:RHA1_ro06180.
PATRIC23211301. VBIRhoJos26306_6226.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMANFKSIEI.
ProtClustDBPRK00053.

Enzyme and pathway databases

BioCycRJOS101510:GJJ1-6177-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ0S3C9_RHOSR
AccessionPrimary (citable) accession number: Q0S3C9
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: May 29, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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