Q0S3C9 (Q0S3C9_RHOSR) Unreviewed, UniProtKB/TrEMBL
Last modified
January 25, 2012.
Version 49.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Alanine racemase HAMAP MF_01201 EC=5.1.1.1 HAMAP MF_01201 | ||||
| Gene names |
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| Organism | Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG97957.1 | ||||
| Taxonomic identifier | 101510 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus |
Protein attributes
| Sequence length | 400 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201 |
| Catalytic activity | L-alanine = D-alanine. HAMAP MF_01201 |
| Cofactor | Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006 |
| Pathway | Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201 Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201 |
| Sequence similarities | Belongs to the alanine racemase family. HAMAP MF_01201 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell shape Cell wall biogenesis/degradation HAMAP MF_01201 Peptidoglycan synthesis HAMAP MF_01201 |
| Ligand | Pyridoxal phosphate HAMAP MF_01201 SAAS SAAS009006 |
| Molecular function | Isomerase HAMAP MF_01201 SAAS SAAS009006 EMBL ABG97957.1 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | alanine metabolic process Inferred from electronic annotation. Source: HAMAP cellular cell wall organizationInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic processInferred from electronic annotation. Source: HAMAP regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | alanine racemase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate bindingInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Sites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Active site | 58 | 1 | Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201 | ||||||
| Active site | 287 | 1 | Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201 | ||||||
Amino acid modifications | |||||||||
| Modified residue | 58 | 1 | N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201 | ||||||
Sequences
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References
| [1] | "The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. Eltis L.D.Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed: 17030794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000431 Genomic DNA. Translation: ABG97957.1. |
| RefSeq | YP_706115.1. NC_008268.1. |
3D structure databases | |
| ProteinModelPortal | Q0S3C9. |
| SMR | Q0S3C9. Positions 28-394. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q0S3C9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4223731. |
| GenomeReviews | Gene locus RHA1_ro06180 in contig CP000431_GR. |
| KEGG | rha:RHA1_ro06180. |
| PATRIC | 23211301. VBIRhoJos26306_6226. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0787. |
| HOGENOM | HBG712172. |
| OMA | EGTPVWV. |
| PhylomeDB | Q0S3C9. |
| ProtClustDB | PRK00053. |
Enzyme and pathway databases | |
| BioCyc | RSP101510:RHA1_RO06180-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01201. Ala_racemase. [Tree] |
| InterPro | IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. [Graphical view] |
| Gene3D | G3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit. |
| KO | K01775. |
| Pfam | PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view] |
| PRINTS | PR00992. ALARACEMASE. |
| SMART | SM01005. Ala_racemase_C. 1 hit. [Graphical view] |
| SUPFAM | SSF50621. Racem_decarbox_C. 1 hit. |
| TIGRFAMs | TIGR00492. Alr. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | Q0S3C9_RHOSR | ||||||||
| Accession | Primary (citable) accession number: Q0S3C9 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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