Q0S3C4 (GCP_RHOSR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	RHA1_ro06185

Organism

Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP]

Taxonomic identifier

101510 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303513

Sequences

	Sequence		Length	Mass (Da)
	Q0S3C4 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 3C8CB2D2FE9FE7C2	FASTA	345	35,230
	10 20 30 40 50 60 MIVMGIESSC DETGVGIVRW NGDGTCELLA DEVASSVEEH ARYGGVVPEV ASRAHLEAIV 70 80 90 100 110 120 PTMRRALAVA GIAKPDALAV TIGPGLAGAL LVGVAAAKAY AAAWDVPFYA VNHLGGHVSV 130 140 150 160 170 180 DTLEHGPMPP CVALLVSGGH THLLHVEDLA KPIVELGTTV DDAAGEAFDK VARLLGLGFP 190 200 210 220 230 240 GGPALDAAAQ DGDRNAIPFP RGMTGPRDAR HDFSFSGLKT AVARYVESKE RAGEVCSVPD 250 260 270 280 290 300 IAASFQEAVA DVLTMKAVRA ARDVGVDTLV LGGGATANSR IRALAEERCA DAGLTLRVPK 310 320 330 340 PRLCTDNGVM IASLGAHLIA GGAAPSLLTV ASDPGLSVAT SQVFS

References

[1]

"The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. , Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R., Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W., Eltis L.D. Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed: 17030794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: RHA1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000431 Genomic DNA. Translation: ABG97962.1.
RefSeq	YP_706120.1. NC_008268.1.
3D structure databases
ProteinModelPortal	Q0S3C4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0S3C4.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4223736.
GenomeReviews	Gene locus RHA1_ro06185 in contig CP000431_GR.
KEGG	rha:RHA1_ro06185.
PATRIC	23211311. VBIRhoJos26306_6231.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q0S3C4.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	RSP101510:RHA1_RO06185-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_RHOSR

Accession

Primary (citable) accession number: Q0S3C4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program