Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q0S345 (Q0S345_RHOSR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glycerol kinase HAMAP MF_00186
EC=2.7.1.30 HAMAP MF_00186
Alternative name(s):
ATP:glycerol 3-phosphotransferase HAMAP MF_00186
Glycerokinase HAMAP MF_00186
Gene names
Name:glpK HAMAP MF_00186
Ordered Locus Names:RHA1_ro06264
OrganismRhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP] EMBL ABG98041.1
Taxonomic identifier101510 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length497 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Key enzyme in the regulation of glycerol uptake and metabolism By similarity. HAMAP MF_00186

Catalytic activity

ATP + glycerol = ADP + sn-glycerol 3-phosphate. HAMAP MF_00186

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1. HAMAP MF_00186

Sequence similarities

Belongs to the FGGY kinase family. HAMAP MF_00186

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding411 – 4155ATP By similarity HAMAP MF_00186

Sites

Binding site141Substrate By similarity HAMAP MF_00186
Binding site181ATP By similarity HAMAP MF_00186
Binding site841Substrate By similarity HAMAP MF_00186
Binding site1361Substrate By similarity HAMAP MF_00186
Binding site2441Substrate By similarity HAMAP MF_00186
Binding site2661ATP By similarity HAMAP MF_00186
Binding site3101ATP; via carbonyl oxygen By similarity HAMAP MF_00186

Sequences

Sequence LengthMass (Da)Tools
Q0S345 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 1E62CDDB76FCD4E4

FASTA49754,290
        10         20         30         40         50         60 
MRVIQYIAAI DQGTTSSRCM IFDHDGAVVS VAQKEHEQFF PRAGWVEHDP KQLWINTREV 

        70         80         90        100        110        120 
VASALAKADL TKRDIAAIGI TNQRETAVVW DRNTGEPVYN AIVWQDTRTD ELCTELGGDE 

       130        140        150        160        170        180 
GSGRYQKRTG LPLSTYFSGP KVRWILDNVD GAREKADAGE LCFGTIDSWI LWHITEGTHV 

       190        200        210        220        230        240 
TDVTNASRTL LMNLETLDWD PEICADFGIP MSMLPEIRSS SEIYGVGRPH GTLPGVPVAG 

       250        260        270        280        290        300 
ILGDQQAATF GQACLSEGEA KNTYGTGNFL LLNTGTTPVH SKHGLLTTVC YKIGDAPAVY 

       310        320        330        340        350        360 
ALEGSVAVTG SLVQWLRDNL GIIESAKDIE DLAKSVEDNG GAYFVPAFSG LFAPRWRPDA 

       370        380        390        400        410        420 
RGAIVGLTRF VNKGHLARAA LEATAYQTRE VIEAMRADSG VELASLKVDG GMVVNETLMQ 

       430        440        450        460        470        480 
FQSDILAVPV IRPVVNETTA LGAAYAAGLA VGFWESEDDI RANWAVDRTW EPAMDEAEST 

       490 
RLYAEWNKAV ERTYDWA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000431 Genomic DNA. Translation: ABG98041.1.
RefSeqYP_706199.1. NC_008268.1.

3D structure databases

ProteinModelPortalQ0S345.
SMRQ0S345. Positions 6-496.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0S345.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4223815.
GenomeReviewsGene locus RHA1_ro06264 in contig CP000431_GR.
KEGGrha:RHA1_ro06264.
PATRIC23211477. VBIRhoJos26306_6314.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0554.
HOGENOMHBG511469.
OMAFEPQINP.
PhylomeDBQ0S345.
ProtClustDBCLSK726606.

Enzyme and pathway databases

BioCycRSP101510:RHA1_RO06264-MONOMER.

Family and domain databases

HAMAPMF_00186. Glycerol_kin.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR005999. Glycerol_kin.
[Graphical view]
KOK00864.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PTHR10196:SF9. Glycerol_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01311. Glycerol_kin. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0S345_RHOSR
AccessionPrimary (citable) accession number: Q0S345
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info