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Q0S0J4

- PGK_RHOSR

UniProt

Q0S0J4 - PGK_RHOSR

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Rhodococcus sp. (strain RHA1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateUniRule annotation
    Binding sitei121 – 1211SubstrateUniRule annotation
    Binding sitei161 – 1611SubstrateUniRule annotation
    Binding sitei211 – 2111ATPUniRule annotation
    Binding sitei299 – 2991ATP; via carbonyl oxygenUniRule annotation
    Binding sitei330 – 3301ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi359 – 3624ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciRJOS101510:GJJ1-7174-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:RHA1_ro07178
    OrganismiRhodococcus sp. (strain RHA1)
    Taxonomic identifieri101510 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
    ProteomesiUP000008710: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 403403Phosphoglycerate kinasePRO_1000009644Add
    BLAST

    Proteomic databases

    PRIDEiQ0S0J4.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi101510.RHA1_ro07178.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0S0J4.
    SMRiQ0S0J4. Positions 4-402.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingUniRule annotation
    Regioni62 – 654Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227107.
    KOiK00927.
    OMAiAGHPVGK.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0S0J4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVQTLDDLL NAGVEGRAVL VRSDLNVPLD GDRITDPGRI IASAPTLKAL    50
    AEAGAKVIVT AHLGRPKGEP DPQYSLAPVA VKLAEVLGRN VQLAGDVVGQ 100
    DALARAEGLT DGDVLLLENI RFDPRETSKD EAERTKLAKA LVELVGDDGA 150
    FVSDGFGVVH RAQASVYEVA KLLPHYAGKL VEAEIKVLGK LTEEPERPYA 200
    VVLGGSKVSD KLAVIEALAP KVDTLVIGGG MYYTFLAAQG VSVGNSLCEE 250
    SMIDTCKALL EQYADVIHIP QDVVIADSFS ADAESKIVSV LEIPDGWMGL 300
    DIGPQSVRRF AAILTSAKTV FWNGPMGVFE FEKFAAGTKG VAEAIIEATG 350
    KGAYSVVGGG DSAAAVRQLG LPEDGFSHIS TGGGASLEYL EGKELPGIAV 400
    LEG 403
    Length:403
    Mass (Da):42,101
    Last modified:September 5, 2006 - v1
    Checksum:i0F03E67F7CAA7C63
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000431 Genomic DNA. Translation: ABG98942.1.
    RefSeqiYP_707100.1. NC_008268.1.

    Genome annotation databases

    EnsemblBacteriaiABG98942; ABG98942; RHA1_ro07178.
    GeneIDi4224728.
    KEGGirha:RHA1_ro07178.
    PATRICi23213335. VBIRhoJos26306_7232.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000431 Genomic DNA. Translation: ABG98942.1 .
    RefSeqi YP_707100.1. NC_008268.1.

    3D structure databases

    ProteinModelPortali Q0S0J4.
    SMRi Q0S0J4. Positions 4-402.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 101510.RHA1_ro07178.

    Proteomic databases

    PRIDEi Q0S0J4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG98942 ; ABG98942 ; RHA1_ro07178 .
    GeneIDi 4224728.
    KEGGi rha:RHA1_ro07178.
    PATRICi 23213335. VBIRhoJos26306_7232.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227107.
    KOi K00927.
    OMAi AGHPVGK.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci RJOS101510:GJJ1-7174-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RHA1.

    Entry informationi

    Entry nameiPGK_RHOSR
    AccessioniPrimary (citable) accession number: Q0S0J4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3