SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0RWM7

- ACDH7_RHOSR

UniProt

Q0RWM7 - ACDH7_RHOSR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Acetaldehyde dehydrogenase 7
Gene
RHA1_ro10116
Organism
Rhodococcus sp. (strain RHA1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD+ and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds By similarity.UniRule annotation

Catalytic activityi

Acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei128 – 1281Acyl-thioester intermediate By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 134NAD By similarity
Nucleotide bindingi159 – 1679NAD By similarity

GO - Molecular functioni

  1. NAD binding Source: UniProtKB-HAMAP
  2. acetaldehyde dehydrogenase (acetylating) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic compound catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRJOS101510:GJJ1-8545-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetaldehyde dehydrogenase 7 (EC:1.2.1.10)
Alternative name(s):
Acetaldehyde dehydrogenase [acetylating] 7
Gene namesi
Ordered Locus Names:RHA1_ro10116
Encoded oniPlasmid pRHL20 Publication
OrganismiRhodococcus sp. (strain RHA1)
Taxonomic identifieri101510 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus
ProteomesiUP000008710: Plasmid pRHL2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 262262Acetaldehyde dehydrogenase 7UniRule annotation
PRO_0000387732Add
BLAST

Proteomic databases

PRIDEiQ0RWM7.

Interactioni

Protein-protein interaction databases

STRINGi101510.RHA1_ro10116.

Structurei

3D structure databases

ProteinModelPortaliQ0RWM7.
SMRiQ0RWM7. Positions 4-261.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG4569.
HOGENOMiHOG000052149.
OMAiTVIHARV.
OrthoDBiEOG6H1PXH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_01657. Ac_ald_DH_ac.
InterProiIPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view]
PfamiPF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view]
PIRSFiPIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTiSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03215. ac_ald_DH_ac. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0RWM7-1 [UniParc]FASTAAdd to Basket

« Hide

MTTKVAIIGS GNIGTDLMFK IQRLSQTLEV AALVGIDPES DGLQRAGRLG    50
IPITADGVAG LLDIPGFDQI SIVFDATSAR AHVANAAALE PFGKQLVDLT 100
PAAIGPYVVP AVNLEENLAA RNVNMVTCGG QATIPMVAAV SHVAPVAYAE 150
IVASIASRSA GPGTRANIDE FTETTSKAIE VVGGAHRGKA IIVLNPADPP 200
LIMRDTILCL IGDADHDAIR DSVHRRVAEV SEYVPGYRLK QDVQITTVTD 250
DVPLSTLGRV SQ 262
Length:262
Mass (Da):27,348
Last modified:September 5, 2006 - v1
Checksum:iEC351AE6B1A07D09
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000433 Genomic DNA. Translation: ABH00309.1.
RefSeqiYP_708467.1. NC_008270.1.

Genome annotation databases

EnsemblBacteriaiABH00309; ABH00309; RHA1_ro10116.
GeneIDi4226099.
KEGGirha:RHA1_ro10116.
PATRICi23215923. VBIRhoJos26306_8524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000433 Genomic DNA. Translation: ABH00309.1 .
RefSeqi YP_708467.1. NC_008270.1.

3D structure databases

ProteinModelPortali Q0RWM7.
SMRi Q0RWM7. Positions 4-261.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 101510.RHA1_ro10116.

Proteomic databases

PRIDEi Q0RWM7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABH00309 ; ABH00309 ; RHA1_ro10116 .
GeneIDi 4226099.
KEGGi rha:RHA1_ro10116.
PATRICi 23215923. VBIRhoJos26306_8524.

Phylogenomic databases

eggNOGi COG4569.
HOGENOMi HOG000052149.
OMAi TVIHARV.
OrthoDBi EOG6H1PXH.

Enzyme and pathway databases

BioCyci RJOS101510:GJJ1-8545-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_01657. Ac_ald_DH_ac.
InterProi IPR003361. Acetaldehyde_dehydrogenase.
IPR015426. Acetylaldehyde_DH_C.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
[Graphical view ]
Pfami PF09290. AcetDehyd-dimer. 1 hit.
PF01118. Semialdhyde_dh. 1 hit.
[Graphical view ]
PIRSFi PIRSF015689. Actaldh_dh_actl. 1 hit.
SMARTi SM00859. Semialdhyde_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR03215. ac_ald_DH_ac. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RHA1.

Entry informationi

Entry nameiACDH7_RHOSR
AccessioniPrimary (citable) accession number: Q0RWM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi