Reviewed, UniProtKB/Swiss-Prot Q0RV72 (G6PI3_RHOSR)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase 3
      Short name=GPI 3
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase 3
      Short name=PGI 3
    Phosphohexose isomerase 3
      Short name=PHI 3

Gene names

Name:	pgi3
Ordered Locus Names:	RHA1_ro11167

Encoded on

Plasmid pRHL3

Organism

Rhodococcus sp. (strain RHA1) [Complete proteome] [HAMAP]

Taxonomic identifier

101510 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	550 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 550	550	Glucose-6-phosphate isomerase 3 HAMAP MF_00473		PRO_0000252639
Sites
	Active site	357	1	Proton donor By similarity
	Active site	388	1	By similarity
	Active site	514	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0RV72-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 0F54949B46249F83	FASTA	550	60,172
	10 20 30 40 50 60 MTATTAQLLT ETTPWLRLSE HSEEIDRSHL RALFASDPDR VDEFTVTAGD LHIDYSKHLI 70 80 90 100 110 120 TRRTRELLLD LARSVDVEGN RDAMLHGEHI NTTENRAVLH TALRLPRDAS LSVDGQDIVT 130 140 150 160 170 180 DVHETLEKMG VFTERLRDGR WRGATGKKIT TVVNIGIGGS DLGPVMVYRA LRHYADAGIS 190 200 210 220 230 240 LRFVSNLDPA DLTDNLRGLD PAATLFIVTS KTFSTLETLT NATAARRWLV SALGEDAVTK 250 260 270 280 290 300 HFVAVSTNAQ PVAEFGIAPE NIFGFWDWVG GRYSVGSAIG LSVMAAIGRE RFTELLDGFH 310 320 330 340 350 360 TIDEHFRTAP PESNAPLLLG MLGVWYSSFR GAQSRAVLPY SNDLVRFPAY LQQLTMESNG 370 380 390 400 410 420 KSVHTDGSPV RCDTGEIFWG EPGTNGQHAF FQLLHQGTRL VPADFIGFAQ STDDLPTMSG 430 440 450 460 470 480 TGSMHDLLMA NFFAQSKVLA FGKTRKEIAA ESASADLIPH KVMPGNRPST TILAPRLTPS 490 500 510 520 530 540 TLGQLIALYE HQVFVQGVVW GIDSFDQWGV ELGKVQALAL APAVAGEAAP CTGDTSTDAL 550 IRTYRRLRHP

References

[1]

"The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse." McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C., Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H., Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H. , Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R., Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W., Eltis L.D. Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006) [PubMed: 17030794] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000434 Genomic DNA. Translation: ABH00814.1.
RefSeq	YP_708972.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4226608.
GenomeReviews	Gene locus RHA1_ro11167 in contig CP000434_GR.
KEGG	rha:RHA1_ro11167.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0RV72.
OMA	Q0RV72. HDASTEG.
Enzyme and pathway databases
BioCyc	RSP101510:RHA1_RO11167-MON.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI3_RHOSR

Accession

Primary (citable) accession number: Q0RV72

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)