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Protein

Glucose-6-phosphate isomerase 3

Gene

pgi3

Organism
Rhodococcus jostii (strain RHA1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathway: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase 4 (pgi4), Glucose-6-phosphate isomerase 2 (pgi2), Glucose-6-phosphate isomerase 1 (pgi1), Glucose-6-phosphate isomerase 3 (pgi3)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei357 – 3571Proton donorUniRule annotation
Active sitei388 – 3881UniRule annotation
Active sitei514 – 5141UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciRJOS101510:GJJ1-9054-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase 3UniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPI 3UniRule annotation
Alternative name(s):
Phosphoglucose isomerase 3UniRule annotation
Short name:
PGI 3UniRule annotation
Phosphohexose isomerase 3UniRule annotation
Short name:
PHI 3UniRule annotation
Gene namesi
Name:pgi3UniRule annotation
Ordered Locus Names:RHA1_ro11167
Encoded oniPlasmid pRHL30 Publication
OrganismiRhodococcus jostii (strain RHA1)
Taxonomic identifieri101510 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesNocardiaceaeRhodococcus
ProteomesiUP000008710 Componenti: Plasmid pRHL3

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 550550Glucose-6-phosphate isomerase 3PRO_0000252639Add
BLAST

Proteomic databases

PRIDEiQ0RV72.

Structurei

3D structure databases

ProteinModelPortaliQ0RV72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiIALHIGY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0RV72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATTAQLLT ETTPWLRLSE HSEEIDRSHL RALFASDPDR VDEFTVTAGD
60 70 80 90 100
LHIDYSKHLI TRRTRELLLD LARSVDVEGN RDAMLHGEHI NTTENRAVLH
110 120 130 140 150
TALRLPRDAS LSVDGQDIVT DVHETLEKMG VFTERLRDGR WRGATGKKIT
160 170 180 190 200
TVVNIGIGGS DLGPVMVYRA LRHYADAGIS LRFVSNLDPA DLTDNLRGLD
210 220 230 240 250
PAATLFIVTS KTFSTLETLT NATAARRWLV SALGEDAVTK HFVAVSTNAQ
260 270 280 290 300
PVAEFGIAPE NIFGFWDWVG GRYSVGSAIG LSVMAAIGRE RFTELLDGFH
310 320 330 340 350
TIDEHFRTAP PESNAPLLLG MLGVWYSSFR GAQSRAVLPY SNDLVRFPAY
360 370 380 390 400
LQQLTMESNG KSVHTDGSPV RCDTGEIFWG EPGTNGQHAF FQLLHQGTRL
410 420 430 440 450
VPADFIGFAQ STDDLPTMSG TGSMHDLLMA NFFAQSKVLA FGKTRKEIAA
460 470 480 490 500
ESASADLIPH KVMPGNRPST TILAPRLTPS TLGQLIALYE HQVFVQGVVW
510 520 530 540 550
GIDSFDQWGV ELGKVQALAL APAVAGEAAP CTGDTSTDAL IRTYRRLRHP
Length:550
Mass (Da):60,172
Last modified:September 5, 2006 - v1
Checksum:i0F54949B46249F83
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000434 Genomic DNA. Translation: ABH00814.1.
RefSeqiWP_011600441.1. NC_008271.1.
YP_708972.1. NC_008271.1.

Genome annotation databases

EnsemblBacteriaiABH00814; ABH00814; RHA1_ro11167.
GeneIDi4226608.
KEGGirha:RHA1_ro11167.
PATRICi23216850. VBIRhoJos26306_8987.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000434 Genomic DNA. Translation: ABH00814.1.
RefSeqiWP_011600441.1. NC_008271.1.
YP_708972.1. NC_008271.1.

3D structure databases

ProteinModelPortaliQ0RV72.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ0RV72.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABH00814; ABH00814; RHA1_ro11167.
GeneIDi4226608.
KEGGirha:RHA1_ro11167.
PATRICi23216850. VBIRhoJos26306_8987.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261371.
KOiK01810.
OMAiIALHIGY.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
BioCyciRJOS101510:GJJ1-9054-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RHA1.

Entry informationi

Entry nameiG6PI3_RHOJR
AccessioniPrimary (citable) accession number: Q0RV72
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: September 5, 2006
Last modified: June 24, 2015
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.