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Protein

Glutamate decarboxylase

Gene

gadB

Organism
Frankia alni (strain ACN14a)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciFALN326424:GJ82-375-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadBImported
Ordered Locus Names:FRAAL0380Imported
OrganismiFrankia alni (strain ACN14a)Imported
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
ProteomesiUP000000657: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi326424.FRAAL0380.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0RTP2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALHGKASGS QAEQTVDVRP QLVRPGEDVV VPRFRIPRES ISPETAYQIV
60 70 80 90 100
HDELMLDGNA RLNLATFVTT WMDPQADRLM AECASKNMID KDEYPQTAEL
110 120 130 140 150
EKRCVNILAD LWHAPDSEHA VGCSTTGSSE ACMLAGLALL RRWRARRRAA
160 170 180 190 200
GAPADRPNLV MGVNVQVCWD KFARYWDVEP RLVPMAPGRT HLTADEAAAR
210 220 230 240 250
CDENTIGVVA ILGSTFDGSY EPVAEIAAAL DRLAAAGGPD VPVHVDGASG
260 270 280 290 300
GFVAPFCDPE LVWDFQLDRV VSINASGHKY GLVYPGVGWV LWRDRAHLPD
310 320 330 340 350
ELVFEVDYLG GKMPTFSLNF SRPGAQVVTQ YYTLLQLGFA GYRRVAQACR
360 370 380 390 400
DNARWLADEV ARMGPFELVS DGSGIPAFAF RLRDEITDYT VFDISELLRT
410 420 430 440 450
RGWLVPAYRF PPDLTDLAVL RIVVRHEFSR DLAGLLVADL RRVVDRLSGA
460
GRPLPPPPPD GEAASFHH
Length:468
Mass (Da):51,585
Last modified:September 5, 2006 - v1
Checksum:i1EDE4E6754EF71D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA. Translation: CAJ59056.1.
RefSeqiWP_011601637.1. NC_008278.1.
YP_710668.1. NC_008278.1.

Genome annotation databases

GeneIDi4237203.
KEGGifal:FRAAL0380.
PATRICi21910739. VBIFraAln347_0339.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA. Translation: CAJ59056.1.
RefSeqiWP_011601637.1. NC_008278.1.
YP_710668.1. NC_008278.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi326424.FRAAL0380.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4237203.
KEGGifal:FRAAL0380.
PATRICi21910739. VBIFraAln347_0339.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciFALN326424:GJ82-375-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ACN14aImported.

Entry informationi

Entry nameiQ0RTP2_FRAAA
AccessioniPrimary (citable) accession number: Q0RTP2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: February 4, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.