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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Enzyme and pathway databases

BioCyciFALN326424:GJ82-1056-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:FRAAL1072
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11411141DNA-directed RNA polymerase subunit betaPRO_0000300320Add
BLAST

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL1072.

Structurei

3D structure databases

ProteinModelPortaliQ0RRT0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 3 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0RRT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASRSSSRI SFAKIIEPLE VPDLLALQTQ SFDWLIGSDA WAERVQEAID
60 70 80 90 100
SGRDDVPITS GLEEVFEEIS PIEDFSGSMS LSFRDHRFEP PKYSVEECKD
110 120 130 140 150
KDMTFSAPLF VTAEFTNNTT GEIKSQTVFM GDFPLMTPKG TFVINGTERV
160 170 180 190 200
VVSQLVRSPG VYFERSLDKA SDKDLYSCKV IPSRGAWLEF EIDKRDTVGV
210 220 230 240 250
RIDRKRRQSV TVLLKALGWD EARILERFGD FPSMRITLEK DHTASQDDAL
260 270 280 290 300
LDIYRKLRPG EPPTRESAQT LLENLFFNPK RYDLAKVGRY KVNKKLTLEI
310 320 330 340 350
AHDVGVLTED DIVRTIEYVV KLHAGADPAE YEVDDIDHFG NRRLRTVGEL
360 370 380 390 400
IQNQVRLGLA RMERVVRERM TTQDVEAITP QTLINIRPVV ASIKEFFGTS
410 420 430 440 450
QLSQFMDQTN PLAGLTHKRR LSALGPGGLS RERAGFEVRD VHPSHYGRMC
460 470 480 490 500
PIETPEGPNI GLIGSLSTFA RVNPFGFVET PYRKVVNGRV TDQIDYLTAD
510 520 530 540 550
EEDRHVKAQA NTPLSPDGTF AEDRVLVRRK GGEVEFIPPD EVDYMDVSPR
560 570 580 590 600
QMVSVATAMI PFLEHDDANR ALMGSNMQRQ SVPLLRSEAP LVGTGMEARA
610 620 630 640 650
AKDAGDVVVC VQAGVVEDLS ADYITVMHDD GTRRTYRLAK FRRSNQGTCI
660 670 680 690 700
NQKPIVFEGD RVEAGQVIAD GPCTDNGEMA LGKNLLVAFM PWEGHNYEDA
710 720 730 740 750
IILSQRLVQD DVLSSIHIEE HEVDARDTKL GPEEITRDIP NVAEEVLADL
760 770 780 790 800
DERGIIRIGA EVSPGDVLVG KVTPKGETEL TPEERLLRAI FGEKAREVRD
810 820 830 840 850
TSLKVPHGES GKVIGVRVFS REDGDELPPG VNELVRVYVA QKRKITDGDK
860 870 880 890 900
LAGRHGNKGV IAKILPQEDM PFLEDGTPVD IVLNPHGVPR RMNIGQILET
910 920 930 940 950
HLGWVAKTGW QVDAGTEDWK ERLRGIGADS STPGTNVATP VFDGAREEEI
960 970 980 990 1000
TGLLDSTLPN RDGVQLIGSS GKATLFDGRT GEPYPYPVAV GYIYILKLLH
1010 1020 1030 1040 1050
LVDDKIHARS TGPYSMITQQ PLGGKAQFGG QRFGEMEVWA LEAYGAAYAL
1060 1070 1080 1090 1100
QELLTIKSDD VVGRVKVYEA IVKGENIPEP GIPESFKVLI KEMQSLCLNV
1110 1120 1130 1140
EVLSSDGVQI EMRDTDEDVF RAAEELGIDL SRREPSSVEE V
Length:1,141
Mass (Da):126,703
Last modified:September 5, 2006 - v1
Checksum:iE7D82B636D3F01FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA. Translation: CAJ59737.1.
RefSeqiWP_011602294.1. NC_008278.1.

Genome annotation databases

KEGGifal:FRAAL1072.
PATRICi21911999. VBIFraAln347_0963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA. Translation: CAJ59737.1.
RefSeqiWP_011602294.1. NC_008278.1.

3D structure databases

ProteinModelPortaliQ0RRT0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi326424.FRAAL1072.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGifal:FRAAL1072.
PATRICi21911999. VBIFraAln347_0963.

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.
OrthoDBiEOG6M9DS6.

Enzyme and pathway databases

BioCyciFALN326424:GJ82-1056-MONOMER.

Family and domain databases

Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 1 hit.
HAMAPiMF_01321. RNApol_bact_RpoB.
InterProiIPR010243. DNA-dir_RNA_pol_bsu.
IPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 3 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ACN14a.

Entry informationi

Entry nameiRPOB_FRAAA
AccessioniPrimary (citable) accession number: Q0RRT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 5, 2006
Last modified: November 11, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.