Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q0RRS9 (RPOC_FRAAA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'
Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:FRAAL1073
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP]
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia ›

Protein attributes

Sequence length1296 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-dependent

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: HAMAP

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12961296DNA-directed RNA polymerase subunit beta' HAMAP-Rule MF_01322
PRO_0000308835

Sequences

Sequence LengthMass (Da)Tools
Q0RRS9 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 05031E4EEEB0CD08

FASTA1,296144,064
        10         20         30         40         50         60 
MLDVNFFDEL RIGLATADDI RQWSHGEVKK PETINYRTLK PEKDGLFCEK IFGPTRDWEC 

        70         80         90        100        110        120 
YCGKYKRVRF KGIICERCGV EVTRAKVRRE RMGHIELAAP VTHIWYFKGV PSRLGYLLDL 

       130        140        150        160        170        180 
APKDLEKVIY FAAYMITKVD AEARHRDLPT LEARMGVEKQ QLEDKKNADV ETRQKRLETD 

       190        200        210        220        230        240 
LAQLEAEGAK GDARRKVRES AEREMRQIRD RAQRKIDDLD RVFDRFKNMK VQDLEPDELL 

       250        260        270        280        290        300 
YRELRDRFGQ YFDGGMGAEA LQRRLADFDL AAEAESLRET IRSGKGQKKA RALKRLKVVS 

       310        320        330        340        350        360 
AFLNTRNSPM GMVLDCVPVI PPDLRPMVQL DGGRFATSDL NDLYRRVINR NNRLKRLLDL 

       370        380        390        400        410        420 
GAPEIIVNNE KRMLQEAVDA LFDNGRRGRP VTGPGNRPLK SLSDMLKGKQ GRFRQNLLGK 

       430        440        450        460        470        480 
RVDYSGRSVI VVGPQLKLHQ CGLPKQMALE LFKPFVMKRL VDLNHAQNIK SAKRMVERAR 

       490        500        510        520        530        540 
PVVWDVLEEV ITEHPVLLNR APTLHRLGIQ AFEPQLVEGK AIQIHPLVCT AFNADFDGDQ 

       550        560        570        580        590        600 
MAVHLPLSAE AQAEARILML SSNNILSPAS GRPLAMPSLD MVTGVFHLST LAEGAVGEGR 

       610        620        630        640        650        660 
AFSSVAEAQM AFDAREIALQ ARISVRLRDT TPPSDWVPPA DWVTGDVFTL ETTFGRCLLN 

       670        680        690        700        710        720 
EALPEGYPFI NAQLNKKAQA AIVNDLAERY PKIQVAATLD ALKSAGFYWA TRSGVTVAIE 

       730        740        750        760        770        780 
DVVAPPNKAE ILDDYEQRAD RVQKQFDRGF LSDEERRSEL VQIWTEATNK IAEAMEKNFP 

       790        800        810        820        830        840 
QTNPVYVLVN SGAAGNMMQI RQLAGMRGLV SNPKGEIIPR PIKANFREGL TVLEYFISTH 

       850        860        870        880        890        900 
GARKGLADTA LRTADSGYLT RRLVDVSQDV IVREEDCGTE RGILTRIARR GADGVLVRDR 

       910        920        930        940        950        960 
YAETSAYART LASDAVDEHG EIIVPAGTDA GDVAIGQIIE AGIESVRVRS ALTCESRMGV 

       970        980        990       1000       1010       1020 
CAQCYGRSLA TGKLVDVGEA VGIVAAQSIG EPGTQLTMRT FHSGGVAGDD ITQGLPRVVE 

      1030       1040       1050       1060       1070       1080 
LFEARSPKGK APITEVSGRV KIEETEKTFK VVVVPDDGSE EIAYPVSRRS RLRVREGDRI 

      1090       1100       1110       1120       1130       1140 
EVGNQIVDGA VDPHEVLRIL GPRQVQLHLV DQVQEVYRSQ GVSIHDKHIE IIIRQMLKRV 

      1150       1160       1170       1180       1190       1200 
NVLESGETNL LPGELCERAR FESENRRVVE SGGQPASARP VLMGITKASL ATESWLSAAS 

      1210       1220       1230       1240       1250       1260 
FQETTRVLTD AAINARSDSL VGLKENVIIG KLIPAGTGIS RYRNIRVEPT EEARAAMYSV 

      1270       1280       1290 
GAYEDGGSVE YGAFGTGSGQ AVPLDEFDYR SSGDFR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT573213 Genomic DNA. Translation: CAJ59738.1.
RefSeqYP_711332.1. NC_008278.1.

3D structure databases

ProteinModelPortalQ0RRS9.
SMRQ0RRS9. Positions 9-136.
ModBaseSearch...

Protein-protein interaction databases

STRING326424.FRAAL1073.

Proteomic databases

PRIDEQ0RRS9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4232670.
KEGGfal:FRAAL1073.
PATRIC21912001. VBIFraAln347_0964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0086.
HOGENOMHOG000218387.
KOK03046.
OMADINDKHI.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycFALN326424:GJ82-1057-MONOMER.

Family and domain databases

Gene3D2.40.40.20. 2 hits.
HAMAPMF_01322. RNApol_bact_RpoC.
InterProIPR009010. Asp_de-COase-like_dom.
IPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_FRAAA
AccessionPrimary (citable) accession number: Q0RRS9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: September 5, 2006
Last modified: May 1, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents