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Protein

DNA-directed RNA polymerase subunit beta'

Gene

rpoC

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Enzyme and pathway databases

BioCyciFALN326424:G1GJE-947-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit beta'UniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit beta'UniRule annotation
Alternative name(s):
RNA polymerase subunit beta'UniRule annotation
Transcriptase subunit beta'UniRule annotation
Gene namesi
Name:rpoCUniRule annotation
Ordered Locus Names:FRAAL1073
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003088351 – 1296DNA-directed RNA polymerase subunit beta'Add BLAST1296

Proteomic databases

PRIDEiQ0RRS9

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL1073

Structurei

3D structure databases

ProteinModelPortaliQ0RRS9
SMRiQ0RRS9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D27 Bacteria
COG0086 LUCA
HOGENOMiHOG000218387
KOiK03046
OMAiYFAAYMI

Family and domain databases

Gene3Di1.10.132.30, 1 hit
HAMAPiMF_01322 RNApol_bact_RpoC, 1 hit
InterProiView protein in InterPro
IPR012754 DNA-dir_RpoC_beta_prime
IPR000722 RNA_pol_asu
IPR006592 RNA_pol_N
IPR007080 RNA_pol_Rpb1_1
IPR007066 RNA_pol_Rpb1_3
IPR007083 RNA_pol_Rpb1_4
IPR007081 RNA_pol_Rpb1_5
IPR038120 Rpb1_funnel_sf
PfamiView protein in Pfam
PF04997 RNA_pol_Rpb1_1, 1 hit
PF00623 RNA_pol_Rpb1_2, 2 hits
PF04983 RNA_pol_Rpb1_3, 1 hit
PF05000 RNA_pol_Rpb1_4, 1 hit
PF04998 RNA_pol_Rpb1_5, 1 hit
SMARTiView protein in SMART
SM00663 RPOLA_N, 1 hit
TIGRFAMsiTIGR02386 rpoC_TIGR, 1 hit

Sequencei

Sequence statusi: Complete.

Q0RRS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDVNFFDEL RIGLATADDI RQWSHGEVKK PETINYRTLK PEKDGLFCEK
60 70 80 90 100
IFGPTRDWEC YCGKYKRVRF KGIICERCGV EVTRAKVRRE RMGHIELAAP
110 120 130 140 150
VTHIWYFKGV PSRLGYLLDL APKDLEKVIY FAAYMITKVD AEARHRDLPT
160 170 180 190 200
LEARMGVEKQ QLEDKKNADV ETRQKRLETD LAQLEAEGAK GDARRKVRES
210 220 230 240 250
AEREMRQIRD RAQRKIDDLD RVFDRFKNMK VQDLEPDELL YRELRDRFGQ
260 270 280 290 300
YFDGGMGAEA LQRRLADFDL AAEAESLRET IRSGKGQKKA RALKRLKVVS
310 320 330 340 350
AFLNTRNSPM GMVLDCVPVI PPDLRPMVQL DGGRFATSDL NDLYRRVINR
360 370 380 390 400
NNRLKRLLDL GAPEIIVNNE KRMLQEAVDA LFDNGRRGRP VTGPGNRPLK
410 420 430 440 450
SLSDMLKGKQ GRFRQNLLGK RVDYSGRSVI VVGPQLKLHQ CGLPKQMALE
460 470 480 490 500
LFKPFVMKRL VDLNHAQNIK SAKRMVERAR PVVWDVLEEV ITEHPVLLNR
510 520 530 540 550
APTLHRLGIQ AFEPQLVEGK AIQIHPLVCT AFNADFDGDQ MAVHLPLSAE
560 570 580 590 600
AQAEARILML SSNNILSPAS GRPLAMPSLD MVTGVFHLST LAEGAVGEGR
610 620 630 640 650
AFSSVAEAQM AFDAREIALQ ARISVRLRDT TPPSDWVPPA DWVTGDVFTL
660 670 680 690 700
ETTFGRCLLN EALPEGYPFI NAQLNKKAQA AIVNDLAERY PKIQVAATLD
710 720 730 740 750
ALKSAGFYWA TRSGVTVAIE DVVAPPNKAE ILDDYEQRAD RVQKQFDRGF
760 770 780 790 800
LSDEERRSEL VQIWTEATNK IAEAMEKNFP QTNPVYVLVN SGAAGNMMQI
810 820 830 840 850
RQLAGMRGLV SNPKGEIIPR PIKANFREGL TVLEYFISTH GARKGLADTA
860 870 880 890 900
LRTADSGYLT RRLVDVSQDV IVREEDCGTE RGILTRIARR GADGVLVRDR
910 920 930 940 950
YAETSAYART LASDAVDEHG EIIVPAGTDA GDVAIGQIIE AGIESVRVRS
960 970 980 990 1000
ALTCESRMGV CAQCYGRSLA TGKLVDVGEA VGIVAAQSIG EPGTQLTMRT
1010 1020 1030 1040 1050
FHSGGVAGDD ITQGLPRVVE LFEARSPKGK APITEVSGRV KIEETEKTFK
1060 1070 1080 1090 1100
VVVVPDDGSE EIAYPVSRRS RLRVREGDRI EVGNQIVDGA VDPHEVLRIL
1110 1120 1130 1140 1150
GPRQVQLHLV DQVQEVYRSQ GVSIHDKHIE IIIRQMLKRV NVLESGETNL
1160 1170 1180 1190 1200
LPGELCERAR FESENRRVVE SGGQPASARP VLMGITKASL ATESWLSAAS
1210 1220 1230 1240 1250
FQETTRVLTD AAINARSDSL VGLKENVIIG KLIPAGTGIS RYRNIRVEPT
1260 1270 1280 1290
EEARAAMYSV GAYEDGGSVE YGAFGTGSGQ AVPLDEFDYR SSGDFR
Length:1,296
Mass (Da):144,064
Last modified:September 5, 2006 - v1
Checksum:i05031E4EEEB0CD08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA Translation: CAJ59738.1
RefSeqiWP_011602295.1, NC_008278.1

Genome annotation databases

KEGGifal:FRAAL1073

Similar proteinsi

Entry informationi

Entry nameiRPOC_FRAAA
AccessioniPrimary (citable) accession number: Q0RRS9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: September 5, 2006
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health