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Q0RRG0 (DEOC_FRAAA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxyribose-phosphate aldolase

Short name=DERA
EC=4.1.2.4
Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase
Short name=Deoxyriboaldolase
Gene names
Name:deoC
Ordered Locus Names:FRAAL1197
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP]
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP-Rule MF_00114

Catalytic activity

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP-Rule MF_00114

Pathway

Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP-Rule MF_00114

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00114.

Sequence similarities

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbohydrate catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

deoxyribonucleotide catabolic process

Inferred from electronic annotation. Source: InterPro

deoxyribose phosphate catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiondeoxyribose-phosphate aldolase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 227227Deoxyribose-phosphate aldolase HAMAP-Rule MF_00114
PRO_1000117545

Sites

Active site1611Schiff-base intermediate with acetaldehyde By similarity
Active site1911 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0RRG0 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 5B6C00FDDBB6D614

FASTA22723,377
        10         20         30         40         50         60 
MRRAEVARLI DHTLLAPAAT DEEVLALCAE AARLGVGAVC VAPTHVYLAA ASTYRSSHEA 

        70         80         90        100        110        120 
EPAFAVASVI GFPHGTHLTV IKAEEARRAV ADGATEIDMV IDIANALDEN WRAIETEISE 

       130        140        150        160        170        180 
VRLSVPPHVI LKVILETALL PDANIIAACR AAEAGGAEFV KTSTGFHPAG GASVRAVRAM 

       190        200        210        220 
AEAVGGRLGI KASGGIRTAE KAKDMLEAGA TRLGLSASAD VLAGFPA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573213 Genomic DNA. Translation: CAJ59859.1.
RefSeqYP_711452.1. NC_008278.1.

3D structure databases

ProteinModelPortalQ0RRG0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326424.FRAAL1197.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4236457.
KEGGfal:FRAAL1197.
PATRIC21912233. VBIFraAln347_1080.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0274.
HOGENOMHOG000241645.
KOK01619.
OrthoDBEOG6QZMW5.

Enzyme and pathway databases

BioCycFALN326424:GJ82-1177-MONOMER.
UniPathwayUPA00002; UER00468.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_00114. DeoC_type1.
InterProIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
IPR028581. DeoC_typeI.
[Graphical view]
PANTHERPTHR10889. PTHR10889. 1 hit.
PfamPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFPIRSF001357. DeoC. 1 hit.
TIGRFAMsTIGR00126. deoC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDEOC_FRAAA
AccessionPrimary (citable) accession number: Q0RRG0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways