ID   Q0RRB5_FRAAA            Unreviewed;       824 AA.
AC   Q0RRB5;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=Putative serine/threonine protein kinase G-protein beta WD-40 repeat {ECO:0000313|EMBL:CAJ59905.2};
DE            EC=2.7.10.1 {ECO:0000313|EMBL:CAJ59905.2};
GN   OrderedLocusNames=FRAAL1244 {ECO:0000313|EMBL:CAJ59905.2};
OS   Frankia alni (strain DSM 45986 / CECT 9034 / ACN14a).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=326424 {ECO:0000313|EMBL:CAJ59905.2, ECO:0000313|Proteomes:UP000000657};
RN   [1] {ECO:0000313|EMBL:CAJ59905.2, ECO:0000313|Proteomes:UP000000657}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACN14a {ECO:0000313|Proteomes:UP000000657};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA   Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA   Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA   Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA   Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA   Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA   Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; CT573213; CAJ59905.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q0RRB5; -.
DR   STRING; 326424.FRAAL1244; -.
DR   KEGG; fal:FRAAL1244; -.
DR   eggNOG; COG0515; Bacteria.
DR   eggNOG; COG2319; Bacteria.
DR   HOGENOM; CLU_000288_135_4_11; -.
DR   Proteomes; UP000000657; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR22847:SF637; WD REPEAT DOMAIN 5; 1.
DR   PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00220; S_TKc; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 6.
DR   PROSITE; PS50082; WD_REPEATS_2; 7.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 7.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:CAJ59905.2}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000657};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Serine/threonine-protein kinase {ECO:0000313|EMBL:CAJ59905.2};
KW   Transferase {ECO:0000313|EMBL:CAJ59905.2};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   TRANSMEM        401..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..257
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REPEAT          486..520
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          531..572
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          576..617
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          621..662
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          666..707
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          711..745
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          756..797
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          269..394
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  86804 MW;  DCCB1918729B8328 CRC64;
     MGTVYLGRGR PGVTGYAGRL VAVKVIRPDL ARVPEFRARF RREADIARRV ARFCTAEVLD
     VVDPPDGLPY LVTEYIDGLT LAQSVAAEGP LRSADLERLA VSVAAALTSI HGAGLVHRDL
     KPSNVLLSSL GPRVIDFGIA RALDAQTMLS QEIQRVGTPA FMAPEQANGE PVSAAADVFA
     WGGLVTYAGT GSFPFGDGPT PVQLYRVVHR EPLLDGLDPA LRPIVEEAMR KDPAARPTAQ
     ELFLRLVGMG PSTHPDPDVT RVIRSAAPML APPQRAGTDG GGSSLGAKPT GRVRPRPADP
     ARPATSPDHA LDTPDRSPGA AAQGWPGDPA AARADLGAAG GWPPPTDDRG GPPSAAGPGH
     RGPAVGDPAR GGLDAGPAGA GAADDPGAPS RRRGRWDRRR IALLAAPILA VLLIAALMPL
     ALTTGGGQRP SREETAARVA LAAEAVRNSD ADLAARLSLA AYRISPVREA RAALRTSFAA
     ATASVLTGHT ASALGVDISP NGRLLASTGA DDLVQLWDIS DRAHPVKLST LTRHTSWVLD
     AAFSPDGRTL ATVSYDRSAI LWDISDPRHP AELAVIHGHN GWVLDAAFSP DGRTLATSGY
     DNTARLWDVT DPRHPTALSV LDRHTSWVNE VAFSPDGHLL ATASADRTAR LWDITDPRRP
     RPLAAITAHT DYVWTVAFSP DGRRLATGAY DGTARLWDIT NPSRPAATAS FPADEKWVFD
     LAFSPDGRTL ATAGWDTTVH LWDVSGTGRP ASVGTINGHG DWIQALAWTP DGSGIATASD
     DYTVRISRID DASLIAAACA DPSKQIDDAE WQRHIADVPY QPVC
//