Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein translocase subunit SecA

Gene

secA

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: May bind 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi964ZincUniRule annotation1
Metal bindingi966ZincUniRule annotation1
Metal bindingi975ZincUniRule annotation1
Metal bindingi976ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi100 – 107ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyciFALN326424:G1GJE-1163-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein translocase subunit SecAUniRule annotation
Gene namesi
Name:secAUniRule annotation
Ordered Locus Names:FRAAL1306
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation
  • Cytoplasm UniRule annotation
  • Note: Distribution is 50-50.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003183521 – 987Protein translocase subunit SecAAdd BLAST987

Proteomic databases

PRIDEiQ0RR55

Interactioni

Subunit structurei

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL1306

Structurei

3D structure databases

ProteinModelPortaliQ0RR55
SMRiQ0RR55
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SecA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CI6 Bacteria
COG0653 LUCA
HOGENOMiHOG000218168
KOiK03070
OMAiFEYDEVM

Family and domain databases

HAMAPiMF_01382 SecA, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR004027 SEC_C_motif
IPR000185 SecA
IPR020937 SecA_CS
IPR011115 SecA_DEAD
IPR014018 SecA_motor_DEAD
IPR011130 SecA_preprotein_X-link_dom
IPR011116 SecA_Wing/Scaffold
IPR036266 SecA_Wing/Scaffold_sf
IPR036670 SecA_X-link_sf
PANTHERiPTHR30612 PTHR30612, 2 hits
PfamiView protein in Pfam
PF02810 SEC-C, 1 hit
PF07517 SecA_DEAD, 1 hit
PF01043 SecA_PP_bind, 1 hit
PF07516 SecA_SW, 1 hit
PRINTSiPR00906 SECA
SMARTiView protein in SMART
SM00957 SecA_DEAD, 1 hit
SM00958 SecA_PP_bind, 1 hit
SUPFAMiSSF52540 SSF52540, 3 hits
SSF81767 SSF81767, 1 hit
SSF81886 SSF81886, 2 hits
TIGRFAMsiTIGR00963 secA, 1 hit
PROSITEiView protein in PROSITE
PS01312 SECA, 1 hit
PS51196 SECA_MOTOR_DEAD, 1 hit

Sequencei

Sequence statusi: Complete.

Q0RR55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLDKILRAG EGRILRKLKA IAEQVNLIED DFTGLSDGEL RGMTDEFRQR
60 70 80 90 100
VAEGKESLDD LLPEAFAAVR EAARRTLGQR HFDVQIMGGA ALHLGNIAEM
110 120 130 140 150
KTGEGKTLVS TLPAYLNALA GKGVHIVTVN DYLAQRDAEN MGRVHRFLGL
160 170 180 190 200
TVGVIHPQMP PPVRRAQYAC DITYGTNNEF GFDYLRDNMA WSADELVQRG
210 220 230 240 250
HNFAVVDEVD SILIDEARTP LIISGPADNP TRWYTEFARI APLLERDVDY
260 270 280 290 300
EVEEGKRTVA ITESGVEKVE DQLGIENLYE SVNTPLVGYL NNSLKAKELY
310 320 330 340 350
KRDKDYIVTD GEVLIVDEFT GRVLHGRRYS EGMHQAIEAK EKVEIKQENQ
360 370 380 390 400
TLATITLQNY FRLYDKLSGM TGTAMTEAAE FHQIYALGVV PIPTNKPMIR
410 420 430 440 450
NDQPDVVYKT EIAKFDAVVE DIAERHEKGQ PVLVGTTSVE KSEYLSKQLT
460 470 480 490 500
KRGVPHEVLN AKHHEREATI IAEAGRKGAV TVATNMAGRG TDIMLGGNPE
510 520 530 540 550
FIAQAELRQR GLSPIETPED YEAAWQEALE KARQSVKTEH EDVVEAGGLY
560 570 580 590 600
VLGTERHESR RIDNQLRGRA GRQGDHGESR FYLSLGDDLM RLFNAAAVEG
610 620 630 640 650
IMDRLNIPED VPIESKIVTR AIRSAQTQVE GQNFEIRKNV LKYDEVMNKQ
660 670 680 690 700
RTVIYEERRK VLDGADLHEQ VRHFVDDTVE GYVRGATADG YPEEWDLDTL
710 720 730 740 750
WTALGQLYPV GVEAPDTDDR DGLTTDHLLE DVQADAQEAY DRRELDLGEG
760 770 780 790 800
ADGEPIMREL ERRVVLAVLD RKWREHLYEM DYLQEGIGLR AMGQRDPLVE
810 820 830 840 850
YQREGFDMFQ TMMEGIKEES VRLLFNVEVQ IAGQETEAAP AENVAVAPAP
860 870 880 890 900
PAGAAALPAA VAPLALPDAA EDDRAAARRT PPEVPAAPAP PAAPPVFVKG
910 920 930 940 950
LEPRRPTGGL RYTAPSVDGG AGPVTILDSG AESPVAGGAA RAARGPAGGS
960 970 980
AAGASARPAR NAPCPCGSGR KYKRCHGDPA RRNAEAE
Length:987
Mass (Da):108,780
Last modified:September 5, 2006 - v1
Checksum:i55EBB2B74FCDDB28
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA Translation: CAJ59967.1
RefSeqiWP_011602504.1, NC_008278.1

Genome annotation databases

KEGGifal:FRAAL1306

Similar proteinsi

Entry informationi

Entry nameiSECA_FRAAA
AccessioniPrimary (citable) accession number: Q0RR55
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 5, 2006
Last modified: April 25, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health