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Protein

60 kDa chaperonin 2

Gene

groL2

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 2UniRule annotation
Alternative name(s):
GroEL protein 2UniRule annotation
Protein Cpn60 2UniRule annotation
Gene namesi
Name:groL2UniRule annotation
Synonyms:groEL2UniRule annotation
Ordered Locus Names:FRAAL1699
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003320031 – 54260 kDa chaperonin 2Add BLAST542

Proteomic databases

PRIDEiQ0RQ25.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL1699.

Structurei

3D structure databases

ProteinModelPortaliQ0RQ25.
SMRiQ0RQ25.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiWTSPKIT.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0RQ25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKMIAFDEE ARRGLERGMN QLADAVRVTL GPKGRNVVLE KKWGVPTITN
60 70 80 90 100
DGVSIAKEIE LEDPYEKIGA ELVKEVAKKT NDVAGDGTTT ATILAQALVR
110 120 130 140 150
EGLRNVAAGA NPLGLKKGIE VAVERVSEEL SKQAKEVETK EQIASTASIS
160 170 180 190 200
AGDSAIGGLI AEALDKVGKE GVVTVEESNT FGLELELTEG MRFDKGYISP
210 220 230 240 250
YFVTDADRQE AVLDDPYILI VNSKIAAVKD LLPLLEKVMQ TSKPLVIISE
260 270 280 290 300
DVEGEALATL VVNKIRGTFK SVAVKAPGFG DRRKAILGDI AILTGGQVIS
310 320 330 340 350
EDVGLKLEST SLDLLGRARK IVVTKDETTV VEGSGDPDQI AGRVSQIRNE
360 370 380 390 400
IDKSDSDYDR EKLQERLAKL AGGVAVIKVG AATEVELKEK KHRIEDAVSN
410 420 430 440 450
AKAAVEEGIV AGGGVALLQA SITAFEKLDL SGDEATGARI VALALAAPLR
460 470 480 490 500
QIASNAGFEG GVVVEKVRDL PVGHGLNAAT GEYVDLIATG IIDPVKVTRS
510 520 530 540
ALQNAASIAG LFLTVEVVVA DRPSAGAAEG GDGAGAMAGM GF
Length:542
Mass (Da):56,735
Last modified:September 5, 2006 - v1
Checksum:iF4CFA13DECCFF278
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA. Translation: CAJ60352.1.
RefSeqiWP_011602885.1. NC_008278.1.

Genome annotation databases

KEGGifal:FRAAL1699.

Similar proteinsi

Entry informationi

Entry nameiCH602_FRAAA
AccessioniPrimary (citable) accession number: Q0RQ25
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: September 5, 2006
Last modified: November 22, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families