Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q0RPH3 (Q0RPH3_FRAAA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease proteolytic subunit 1 HAMAP MF_00444
EC=3.4.21.92 HAMAP MF_00444
Alternative name(s):
Endopeptidase Clp 1 HAMAP MF_00444
Gene names
Name:clpP1 HAMAP MF_00444 EMBL CAJ60559.1
Ordered Locus Names:FRAAL1910
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP] EMBL CAJ60559.1
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length213 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins By similarity. HAMAP MF_00444

Catalytic activity

Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). HAMAP MF_00444

Subcellular location

Cytoplasm By similarity HAMAP MF_00444.

Sequence similarities

Belongs to the peptidase S14 family. RuleBase RU003567 HAMAP MF_00444

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00444
   LigandATP-binding HAMAP MF_00444
Nucleotide-binding
   Molecular functionHydrolase
Protease
Serine protease HAMAP MF_00444
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processproteolysis

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

serine-type endopeptidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1081 By similarity HAMAP MF_00444
Active site1331 By similarity HAMAP MF_00444

Sequences

Sequence LengthMass (Da)Tools
Q0RPH3 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 0AE93E1E78392856

FASTA21323,107
        10         20         30         40         50         60 
MSNLAVPRLP VPGPELRSPG QGGPAFDDQV FNRLLANRIV FLGSVVEDSI ANAICAQLLL 

        70         80         90        100        110        120 
LNAEDPTRDI FLYINSPGGS VSAGMAIYDT MQFVENDVAT VSLGLAASMG QFLLCAGAPG 

       130        140        150        160        170        180 
KRYSLPHARI MMHQPSGGIG GTASDIAIQA EQMLYTKRMM QERIAFHTGQ PIEQIERDSD 

       190        200        210 
RDRWFTAEEA KDYGFVDHVV QQARQVPSEG PVS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CT573213 Genomic DNA. Translation: CAJ60559.1.
RefSeqYP_712142.1. NC_008278.1.

3D structure databases

ProteinModelPortalQ0RPH3.
SMRQ0RPH3. Positions 25-203.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0RPH3.

Protein family/group databases

MEROPSS14.008.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4235214.
GenomeReviewsGene locus FRAAL1910 in contig CT573213_GR.
KEGGfal:FRAAL1910.
PATRIC21913530. VBIFraAln347_1724.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0740.
HOGENOMHBG558421.
OMANAICAQL.
ProtClustDBCLSK948065.

Family and domain databases

HAMAPMF_00444. ClpP.
[Tree]
InterProIPR023562. Pept_S14/S49.
IPR001907. Pept_S14_ClpP.
IPR018215. Pept_S14_ClpP_AS.
[Graphical view]
KOK01358.
PANTHERPTHR10381. Pept_S14_ClpP. 1 hit.
PfamPF00574. CLP_protease. 1 hit.
[Graphical view]
PRINTSPR00127. CLPPROTEASEP.
PROSITEPS00382. CLP_PROTEASE_HIS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0RPH3_FRAAA
AccessionPrimary (citable) accession number: Q0RPH3
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info