Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q0RPF5 (Q0RPF5_FRAAA) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP-Rule MF_00456

EC=2.7.2.11 HAMAP-Rule MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP-Rule MF_00456
Gene names
Name:proB HAMAP-Rule MF_00456 EMBL CAJ60577.1
Ordered Locus Names:FRAAL1928 EMBL CAJ60577.1
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP] EMBL CAJ60577.1
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP-Rule MF_00456 SAAS SAAS019797

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP-Rule MF_00456 SAAS SAAS019797

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP-Rule MF_00456 SAAS SAAS019797

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00456 SAAS SAAS019797.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP-Rule MF_00456

Contains 1 PUA domain. HAMAP-Rule MF_00456

Contains PUA domain. SAAS SAAS019797

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain270 – 34879PUA By similarity HAMAP-Rule MF_00456
Nucleotide binding166 – 1672ATP By similarity HAMAP-Rule MF_00456

Sites

Binding site101ATP By similarity HAMAP-Rule MF_00456
Binding site471Substrate By similarity HAMAP-Rule MF_00456
Binding site1341Substrate By similarity HAMAP-Rule MF_00456
Binding site1461Substrate; via amide nitrogen By similarity HAMAP-Rule MF_00456

Sequences

Sequence LengthMass (Da)Tools
Q0RPF5 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 16B462B59FB0E61B

FASTA36637,632
        10         20         30         40         50         60 
MADAQRVVVK VGSSSLTTAA GGLDVARLEG LVSALLPRAG QLVLVSSGAI AAGLAPLGLA 

        70         80         90        100        110        120 
RRPRDLATQQ AAASVGQSSL VHSYAAAFGR AGFRVGQVLL TATDVIRRTH YRNARTALDR 

       130        140        150        160        170        180 
LLELGVVPIV NENDAVATQE IRFGDNDRLA AIVAHLVSAD LLVLLSDVDG LYDANPRHGP 

       190        200        210        220        230        240 
ANLLREVRSD ADLAGLTARG TGTAGVGVGG MATKIEAARM AASGGVTAII TSAANAAPVL 

       250        260        270        280        290        300 
RGEEVGTVFH PTGPRRASRL LWLAHATAPE GLLRLDDGAV AAVVRRRASL LPAGVTGIEG 

       310        320        330        340        350        360 
DFSAGDPVDL VDPGGRPVAR GLVAFDAAEL PAMLGRSTAE LAAELGPSYE REIVHRDDLV 


LLLPTR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573213 Genomic DNA. Translation: CAJ60577.1.
RefSeqYP_712160.1. NC_008278.1.

3D structure databases

ProteinModelPortalQ0RPF5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326424.FRAAL1928.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4236727.
KEGGfal:FRAAL1928.
PATRIC21913568. VBIFraAln347_1743.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHOG000246368.
KOK00931.
OMAPPTIASK.
OrthoDBEOG6PGK7G.
ProtClustDBPRK05429.

Enzyme and pathway databases

BioCycFALN326424:GJ82-1893-MONOMER.
UniPathwayUPA00098; UER00359.

Family and domain databases

Gene3D2.30.130.10. 1 hit.
3.40.1160.10. 1 hit.
HAMAPMF_00456. ProB.
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. SSF53633. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsTIGR01027. proB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0RPF5_FRAAA
AccessionPrimary (citable) accession number: Q0RPF5
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)