Q0RNY5 (Q0RNY5_FRAAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uroporphyrinogen decarboxylase RuleBase RU000554
EC=4.1.1.37 RuleBase RU000554

Gene names

Name:	hemE EMBL CAJ60750.1
Ordered Locus Names:	FRAAL2101

Organism

Frankia alni (strain ACN14a) [Complete proteome] [HAMAP] EMBL CAJ60750.1

Taxonomic identifier

326424 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	452 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III By similarity. SAAS SAAS006361
Catalytic activity	Uroporphyrinogen III = coproporphyrinogen + 4 CO2. RuleBase RU000554 SAAS SAAS006361
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen III from 5-aminolevulinate: step 4/4. RuleBase RU000554 Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4. SAAS SAAS006361
Subunit structure	Homodimer By similarity. SAAS SAAS006361
Subcellular location	Cytoplasm By similarity SAAS SAAS006361.
Sequence similarities	Belongs to the uroporphyrinogen decarboxylase family. RuleBase RU004169

Ontologies

Keywords
Biological process	Porphyrin biosynthesis RuleBase RU000554 SAAS SAAS006361
Cellular component	Cytoplasm SAAS SAAS006361
Molecular function	Decarboxylase RuleBase RU000554 SAAS SAAS006361 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	uroporphyrinogen decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0RNY5 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 077433E07B945B82	FASTA	452	47,359
	10 20 30 40 50 60 MPIGVTPVAP AQVRRACNDR GMSVVHIDAG PGSGSASVQT APSGVAVASA RVAPSRDGDT 70 80 90 100 110 120 LHRPGRLASA TGLPLTDAAL RAGAADPCAE AADPRAGVAP RCAAARSADA RRPGLASTAP 130 140 150 160 170 180 FLRACRRDQP ETTPVWFMRQ AGRVLPEYRA LRADVPMLDS CRDPAMITEI TMQPVRRFRP 190 200 210 220 230 240 DAAIFFSDIV VPLVAIGLDI DIVAGVGPVV AEPVRDSARL AALRALEPDD VPYVTQAVRD 250 260 270 280 290 300 LLGELGGTPL IGFAGAPFTL ASYLVEGGPS RNHLRTKAMM YGEPELWHEL LDRLATITTA 310 320 330 340 350 360 FLRVQVDAGV DAVQLFDSWA GALSEDDYRR YVAPHSARVL AAFAGEVPRI HFGVNTGELL 370 380 390 400 410 420 AAMGQVGADV VGVDWRVPLD EAARRIGPGR AVQGNLDPAA VFAPEPVLAA KVGDVLARGA 430 440 450 KAEGHVFNLG HGVLPETDPG VLAHIVDLVH AG

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573213 Genomic DNA. Translation: CAJ60750.1.
RefSeq	YP_712330.1. NC_008278.1.
3D structure databases
ProteinModelPortal	Q0RNY5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0RNY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4231195.
GenomeReviews	Gene locus FRAAL2101 in contig CT573213_GR.
KEGG	fal:FRAAL2101.
PATRIC	21913908. VBIFraAln347_1915.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0407.
HOGENOM	HBG628392.
OMA	PRIHFGV.
PhylomeDB	Q0RNY5.
ProtClustDB	PRK00115.
Family and domain databases
HAMAP	MF_00218. URO_D. [Tree]
InterPro	IPR006361. Uroporphyrinogen_deCO2ase_HemE. IPR000257. Uroporphyrinogen_deCOase. [Graphical view]
KO	K01599.
PANTHER	PTHR21091:SF2. HemE. 1 hit.
Pfam	PF01208. URO-D. 1 hit. [Graphical view]
TIGRFAMs	TIGR01464. HemE. 1 hit.
PROSITE	PS00906. UROD_1. 1 hit. PS00907. UROD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0RNY5_FRAAA

Accession

Primary (citable) accession number: Q0RNY5

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)