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Q0RKT0 (UPPP1_FRAAA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Ordered Locus Names:FRAAL3231
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP]
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Undecaprenyl-diphosphatase 1 HAMAP-Rule MF_01006
PRO_0000290709

Regions

Transmembrane46 – 6621Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane119 – 13921Helical; Potential
Transmembrane153 – 17321Helical; Potential
Transmembrane191 – 21121Helical; Potential
Transmembrane225 – 24521Helical; Potential
Transmembrane256 – 27621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q0RKT0 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 912E36430A50526F

FASTA27829,238
        10         20         30         40         50         60 
MSAISVGQAI ILGVVEGLTE FLPISSTGHL KIAEGLMDIQ VDDKAVVGFT AVIQVGAIAA 

        70         80         90        100        110        120 
VLVYFFADIR RFVTAWGRGL ANPAARTNHD YTFTWWVIYA TIPVVLVGLA AKPLIDGPLA 

       130        140        150        160        170        180 
SLWVVAASLL AGSALMWFAD QYGRHKRGED DLSLPDAMIV GTSQILALLF PGFSRSGATI 

       190        200        210        220        230        240 
STGLIRDLDR VAATRLSFFL SIPALTGAGL YELKDAVGGG VSAAPLAVGT VVSFFVAYAS 

       250        260        270 
IAWLLKFVAR HNFNAFIIYR VAVAVLLAGL LAGGAINA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573213 Genomic DNA. Translation: CAJ61875.1.
RefSeqYP_713442.1. NC_008278.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326424.FRAAL3231.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4231404.
KEGGfal:FRAAL3231.
PATRIC21916000. VBIFraAln347_2956.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAWVIYATI.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycFALN326424:GJ82-3186-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP1_FRAAA
AccessionPrimary (citable) accession number: Q0RKT0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: September 5, 2006
Last modified: February 19, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families