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Q0RHR9 (UPPP3_FRAAA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 3

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 3
Undecaprenyl pyrophosphate phosphatase 3
Gene names
Name:uppP3
Ordered Locus Names:FRAAL4312
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP]
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length297 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 297297Undecaprenyl-diphosphatase 3 HAMAP-Rule MF_01006
PRO_0000290711

Regions

Transmembrane39 – 5921Helical; Potential
Transmembrane89 – 10921Helical; Potential
Transmembrane118 – 13821Helical; Potential
Transmembrane203 – 22321Helical; Potential
Transmembrane237 – 25721Helical; Potential
Transmembrane268 – 28821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q0RHR9 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: D2880E9FB09A3656

FASTA29731,549
        10         20         30         40         50         60 
MNYFEGTVLG LVQGLTEFLP VSSSAHLRIT AALAGWDDPG AAFTAVTQIG TETAVLIYFR 

        70         80         90        100        110        120 
RDIARIVRAW ALSWTRREMR KDTDARVGWL VLLGTIPIGL LGVTLQDAIE GPFRDLRLIA 

       130        140        150        160        170        180 
TTLIVLGLIL GGADWYASKG RPRGRHSLPR PRKTLRDLSV RDGLLYGLAQ SAALIPGVSR 

       190        200        210        220        230        240 
SGATISGGLL LGYTREAAAR YSFLLAMPAV LASGVFELKS IGGDREGGDG EEVSWGPTIV 

       250        260        270        280        290 
ATVVAFATGY AAIAWFLRYI STRSFAPFVL YRVALGLLLL ALLAGGAISA DAGAAAD 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573213 Genomic DNA. Translation: CAJ62954.1.
RefSeqYP_714505.1. NC_008278.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326424.FRAAL4312.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4235234.
KEGGfal:FRAAL4312.
PATRIC21918016. VBIFraAln347_3964.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAIEGPFRD.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycFALN326424:GJ82-4250-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP3_FRAAA
AccessionPrimary (citable) accession number: Q0RHR9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families