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Protein

Glucose-1-phosphate adenylyltransferase

Gene

glgC

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.UniRule annotation

Catalytic activityi

ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei163Alpha-D-glucose 1-phosphate; via amide nitrogenUniRule annotation1
Binding sitei197Alpha-D-glucose 1-phosphate; via carbonyl oxygenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFALN326424:FRAAL_RS19910-MONOMER
UniPathwayiUPA00164

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphate adenylyltransferaseUniRule annotation (EC:2.7.7.27UniRule annotation)
Alternative name(s):
ADP-glucose pyrophosphorylaseUniRule annotation
Short name:
ADPGlc PPaseUniRule annotation
ADP-glucose synthaseUniRule annotation
Gene namesi
Name:glgCUniRule annotation
Ordered Locus Names:FRAAL4553
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000515651 – 412Glucose-1-phosphate adenylyltransferaseAdd BLAST412

Proteomic databases

PRIDEiQ0RH38

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL4553

Structurei

3D structure databases

ProteinModelPortaliQ0RH38
SMRiQ0RH38
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni179 – 180Alpha-D-glucose 1-phosphate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QQ4 Bacteria
COG0448 LUCA
HOGENOMiHOG000278607
KOiK00975
OMAiHCVLGVR

Family and domain databases

Gene3Di3.90.550.10, 1 hit
HAMAPiMF_00624 GlgC, 1 hit
InterProiView protein in InterPro
IPR011831 ADP-Glc_PPase
IPR005836 ADP_Glu_pyroP_CS
IPR023049 GlgC_bac
IPR005835 NTP_transferase_dom
IPR029044 Nucleotide-diphossugar_trans
IPR011004 Trimer_LpxA-like_sf
PfamiView protein in Pfam
PF00483 NTP_transferase, 1 hit
SUPFAMiSSF51161 SSF51161, 1 hit
SSF53448 SSF53448, 1 hit
TIGRFAMsiTIGR02091 glgC, 1 hit
PROSITEiView protein in PROSITE
PS00809 ADP_GLC_PYROPHOSPH_2, 1 hit
PS00810 ADP_GLC_PYROPHOSPH_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q0RH38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPRVLGLV LAGGAGRRLA PLTADRAKPA VPFGGLYRLI DFVLSNLVNA
60 70 80 90 100
GYLRIAVLTQ YKSHSLDRHI TTTWRMSNLL GNYVTPVPAQ QRLGPRWFAG
110 120 130 140 150
SADAIHQSLN LVHDDNPDIV VVFGADHVYR MDPRQMVAQH LDSGAGVTVA
160 170 180 190 200
GLRVPRAEGR SFGVIQTGRD GRIIEAFLEK PADPPGLPGS PEETFASMGN
210 220 230 240 250
YVFSTDVLID ALRKDAADED SRHDMGGDII PMLVAQRAAA VYDFSDNVVP
260 270 280 290 300
GTTARDRGYW RDVGTLDSYF DAQMDLCALD PVFNLYNREW PIFTSVPSLP
310 320 330 340 350
PAKFVHDDPR RTGIAINSIV SNGVIVSGGT VRSAVLSPGV RINSWAEVDR
360 370 380 390 400
AVVLDNAVVG RGAVVRDAIL DKNVHVPPGA QVGVDKDRDR ARGYTVSERG
410
ITVVGKGVTV TD
Length:412
Mass (Da):44,479
Last modified:September 5, 2006 - v1
Checksum:iB4DD59AC740F443C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA Translation: CAJ63195.1
RefSeqiWP_011605671.1, NC_008278.1

Genome annotation databases

KEGGifal:FRAAL4553

Similar proteinsi

Entry informationi

Entry nameiGLGC_FRAAA
AccessioniPrimary (citable) accession number: Q0RH38
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: June 20, 2018
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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