Q0RFB3 (Q0RFB3_FRAAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006 EMBL CAJ63834.1
Ordered Locus Names:	FRAAL5201

Organism

Frankia alni (strain ACN14a) [Complete proteome] [HAMAP] EMBL CAJ63834.1

Taxonomic identifier

326424 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Frankineae › Frankiaceae › Frankia

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL CAJ63834.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0RFB3 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 98CF37FB7116B700	FASTA	504	53,650
	10 20 30 40 50 60 MTSTDHSEEA AVPKPPAGGA TDADAPAGGV LAGGASAGAP MRLWGGRFAG GPAEALARLS 70 80 90 100 110 120 VSVQFDWRLA PYDLLASKSH ARVLHRAGLL DDAELAAMLA AIDDLSDAVA QGRFRPTVED 130 140 150 160 170 180 EDVHTALERG LLERLGALGG KLRAGRSRND QVATDLRLYL REHARQVAAR LTELSQALVT 190 200 210 220 230 240 VAEQHVDTPA PGMTHLQHAQ PISFGHQLLA HVQAFVRDTD RLRDWDRRAS VSALGAGALA 250 260 270 280 290 300 GSSLPLDPRG VAAELGFDRA FDNSLDAVSD RDFAAEFLFV AALIGVHLSR LGEEIVLWTT 310 320 330 340 350 360 REFGWVELDD AFATGSSIMP QKKNPDVAEL ARGKSGRLIG GLTGFLATLK GLPLAYDRDL 370 380 390 400 410 420 QEDKEPVFDA VDTLLLVLPA LTGTVATMRV RRERLAAAAP DGFALATDVA EYLVRRGVPF 430 440 450 460 470 480 RQAHEAVGQL VSWCVAHDVD LDGVSDDDLA VINPLLTPDV RGVLSVSGAL QARSAPGGTA 490 500 PDRVREQLAA LRPVLDRDRA WAVD

References

[1]

"Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography." Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N., Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A., Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P., Goltsman E., Huang Y. , Kopp O.R., Labarre L., Lapidus A., Lavire C., Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J., Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F., Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C., Benson D.R. Genome Res. 17:7-15(2007) [PubMed: 17151343] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT573213 Genomic DNA. Translation: CAJ63834.1.
RefSeq	YP_715368.1. NC_008278.1.
3D structure databases
ProteinModelPortal	Q0RFB3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0RFB3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4237479.
GenomeReviews	Gene locus FRAAL5201 in contig CT573213_GR.
KEGG	fal:FRAAL5201.
PATRIC	21919618. VBIFraAln347_4760.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0165.
HOGENOM	HBG539632.
OMA	MPGRTHL.
PhylomeDB	Q0RFB3.
ProtClustDB	PRK00855.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0RFB3_FRAAA

Accession

Primary (citable) accession number: Q0RFB3

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)