SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0RFB2

- ASSY_FRAAA

UniProt

Q0RFB2 - ASSY_FRAAA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Argininosuccinate synthase

Gene
argG, FRAAL5202
Organism
Frankia alni (strain ACN14a)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei87 – 871Citrulline By similarity
Binding sitei92 – 921Citrulline By similarity
Binding sitei117 – 1171ATP; via amide nitrogen By similarity
Binding sitei119 – 1191Aspartate By similarity
Binding sitei123 – 1231Aspartate By similarity
Binding sitei123 – 1231Citrulline By similarity
Binding sitei124 – 1241Aspartate By similarity
Binding sitei127 – 1271Citrulline By similarity
Binding sitei175 – 1751Citrulline By similarity
Binding sitei259 – 2591Citrulline By similarity
Binding sitei271 – 2711Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 169ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFALN326424:GJ82-5120-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:FRAAL5202
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
ProteomesiUP000000657: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Argininosuccinate synthaseUniRule annotationPRO_1000000396Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL5202.

Structurei

3D structure databases

ProteinModelPortaliQ0RFB2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiKANALYM.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0RFB2-1 [UniParc]FASTAAdd to Basket

« Hide

MTERVVLAYS GGLDTSVAIG WIGAETGAEV VALAVDVGQG GEDLEAIRQR    50
ALTCGAVESI VVDARTEFAE SFVAPAIRSN ALYMDRYPLI SSLSRPIIVK 100
HLVEAAREHG ADAIAHGCTG KGNDQVRFEV GVSALAPGLK VLAPVRDSGM 150
TRDKAIAFAE ERGLPIDVSK RSPYSIDQNL WGRTAECGIL EDPWAQPPED 200
VFVYSADPTV ARTPDEVTIS FTDGVPTGLD GRSLSLAELV AELNTRAGAH 250
GVGRIDMIED RLVGIKSREI YECPAAITLL TAHRDLEDLT LERDVARFKR 300
GVDQRWGEIV YDGLWYSPLK AALDAFVDAA SAGVDGDVRL RLAGGVAQVV 350
GRRSPGSLYD HALATYDAGD QFDQGDARGF IELWGLPTKV WAAREQRLNP 400
Length:400
Mass (Da):43,025
Last modified:September 5, 2006 - v1
Checksum:i36597689C1A63268
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT573213 Genomic DNA. Translation: CAJ63835.1.
RefSeqiYP_715369.1. NC_008278.1.

Genome annotation databases

GeneIDi4237478.
KEGGifal:FRAAL5202.
PATRICi21919620. VBIFraAln347_4761.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT573213 Genomic DNA. Translation: CAJ63835.1 .
RefSeqi YP_715369.1. NC_008278.1.

3D structure databases

ProteinModelPortali Q0RFB2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 326424.FRAAL5202.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 4237478.
KEGGi fal:FRAAL5202.
PATRICi 21919620. VBIFraAln347_4761.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi KANALYM.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci FALN326424:GJ82-5120-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ACN14a.

Entry informationi

Entry nameiASSY_FRAAA
AccessioniPrimary (citable) accession number: Q0RFB2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi