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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Frankia alni (strain ACN14a)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei374Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi173 – 180ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFALN326424:FRAAL_RS25835-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Ordered Locus Names:FRAAL5933
OrganismiFrankia alni (strain ACN14a)
Taxonomic identifieri326424 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000000657 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, CF(1), Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003026501 – 552ATP synthase subunit alphaAdd BLAST552

Proteomic databases

PRIDEiQ0RDB2

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.UniRule annotation

Protein-protein interaction databases

STRINGi326424.FRAAL5933

Structurei

3D structure databases

ProteinModelPortaliQ0RDB2
SMRiQ0RDB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDG Bacteria
COG0056 LUCA
HOGENOMiHOG000130111
KOiK02111
OMAiGNAQIKS

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

Q0RDB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTELSIRPEE IRDALREYVD SFQATSAGRE EVGRVVVTGD GIARVEGLPH
60 70 80 90 100
TMTNELLEFS GGVLGLALNL EIGEIGTVIL GEAEHIEEGQ EVRRTGEILA
110 120 130 140 150
VPVGDGFLGR VVDPLGRPID GLGEIQAEGT RALELQAPTV VQRQPVKEPL
160 170 180 190 200
QTGIKAIDAM TAIGRGQRQL IIGDRQTGKT TVAIDTIINQ RDNWASGDPS
210 220 230 240 250
KQVKCVYVAI GQKKSTIREV VNTLEEAGAL AYTTVVAAPA DEPAGFKYIA
260 270 280 290 300
PYAGSAIAQH WMYNGQHALI VFDDLSKQAE AYRAISLLLR RPPGREAYPG
310 320 330 340 350
DVFYLHSRLL ERCAKLSDEL GGGSLTGLPI IETKASDISA YIPTNVISIT
360 370 380 390 400
DGQIFLESDL FNQGVRPAIN VGTSVSRVGG SAQTKAMKSV AGRLRLDLAQ
410 420 430 440 450
YRELEAFSAF GSDLDKASRD QLARGARLVE LLKQPQNQPY PIERQVVSIW
460 470 480 490 500
AGTTGKVDDV PVADVRRFES EFLDYVGRSH RGIYDAILGS GKLGDDVIQE
510 520 530 540 550
LNSAIAAFKN QFTLSDGKPL VNEAAASPLD PSAVRKESIP VHRAPARTDD

EG
Length:552
Mass (Da):59,541
Last modified:September 5, 2006 - v1
Checksum:iA30361B6AF60B2FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT573213 Genomic DNA Translation: CAJ64558.1
RefSeqiWP_011606993.1, NC_008278.1

Genome annotation databases

KEGGifal:FRAAL5933

Similar proteinsi

Entry informationi

Entry nameiATPA_FRAAA
AccessioniPrimary (citable) accession number: Q0RDB2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 5, 2006
Last modified: June 20, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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