Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0RCJ1

- SYL_FRAAA

UniProt

Q0RCJ1 - SYL_FRAAA

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Frankia alni (strain ACN14a)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei841 – 8411ATPUniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA editing activity Source: InterPro
    2. ATP binding Source: UniProtKB-HAMAP
    3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciFALN326424:GJ82-6107-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
    Alternative name(s):
    Leucyl-tRNA synthetaseUniRule annotation
    Short name:
    LeuRSUniRule annotation
    Gene namesi
    Name:leuSUniRule annotation
    Ordered Locus Names:FRAAL6210
    OrganismiFrankia alni (strain ACN14a)
    Taxonomic identifieri326424 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia
    ProteomesiUP000000657: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10691069Leucine--tRNA ligasePRO_0000334758Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi326424.FRAAL6210.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0RCJ1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi107 – 11812"HIGH" regionAdd
    BLAST
    Motifi838 – 8425"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0495.
    HOGENOMiHOG000200748.
    KOiK01869.
    OMAiKGNPLES.
    OrthoDBiEOG63Z74X.

    Family and domain databases

    Gene3Di1.10.730.10. 1 hit.
    3.40.50.620. 4 hits.
    3.90.740.10. 2 hits.
    HAMAPiMF_00049_B. Leu_tRNA_synth_B.
    InterProiIPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR015413. Methionyl/Leucyl_tRNA_Synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view]
    PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
    PfamiPF08264. Anticodon_1. 1 hit.
    PF13603. tRNA-synt_1_2. 2 hits.
    PF09334. tRNA-synt_1g. 1 hit.
    [Graphical view]
    SUPFAMiSSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 2 hits.

    Sequencei

    Sequence statusi: Complete.

    Q0RCJ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSQGRRTNEL GWHERMSETA EHGTGAANAT ASPSGAVPPS GATATAGTGD     50
    EPGFRYDARL AADIERRWQR RWADEGTFNS PNPVGPLAAG FDEVAGREPF 100
    YIMDMFPYPS GTGLHVGHPL GYIGTDVFAR YLRMSGRHVL HPFGYDAFGL 150
    PAEQYAINTG QHPRTTTDAN IANMRRQLSR LGLGHDTRRE IATTDVGYYR 200
    WTQWIFEQIF DAWYDPQAGR ARPIAELIAE FEAGTRSPAA GPAAGTTAVS 250
    VDAVRAANPT GLPWAELDRV TRRRVVDAHR LAYISEQLVN WCPGLGTVLA 300
    NEEVTAEGRS DIGNYPVFRR PLRQWVLRIT AYAERLVDDL DLVDWSDSIK 350
    QMQRNWIGPS DGAGVEFAVV PPSGSAGAAP GQRIEVYTTR PDTLAGATFL 400
    VLAPEHPQVD ALVADAWPAG TPGAWRFPAG RGPAVGEAAE VAAEEVAAEE 450
    VGAAEVEAAA ADPAWTPRAA VEAYRAFAAR RSDRQRGEEV DRTGVFTGAY 500
    VRNPVGGGLL PVFLADYVLV GYGTGAIMAV PAHDSRDFSF ARAFDLPIPA 550
    VLAPDEQWYA EHRVTPGAPP SAWPEAFGGE GAYLPGPAGT PVLAGLTKPD 600
    AIKTTVRWLE DGGHGRLARS YRLRDWLFSR QRYWGEPFPI VFDDDGLPYA 650
    VPDELLPVEL PEMTDFRPTA MAEDDESDPV PPLARVADWA SVTLDLGDGP 700
    KRYRRETNTM PQWAGSCWYH LRYLDPTNTE RFVDETVERY WLAKPGAAAG 750
    DGGVDLYVGG VEHAVLHLLY ARFWQKVLYD LGHVSSKEPF KRLFNQGYIQ 800
    ADAFTDARGM YVPAAEVKQT DDGRFTHHGA PVDRRSGKMG KSLKNSVSPD 850
    EMYERFGADT LRVYEMAMGP LDADRPWHTD DIVGSHRFLQ RLWRAVVDEG 900
    SGTVAVSDEQ LDAEATRVLH RTIITLAAEY AGLRFNTAVA RLIELTNYVS 950
    KRYGQAATPR ALAEPLVLMV APLAPHIAEE LWTRLGHSES VSRAAFPVGD 1000
    PALAAESERT IPVQVNGKVR FTLQVPDGAA EPVIRELLTA HPDYARQTEG 1050
    RTIKKTIIVP GRIVNIALG 1069
    Length:1,069
    Mass (Da):116,994
    Last modified:September 5, 2006 - v1
    Checksum:i392D3E9F711BC099
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT573213 Genomic DNA. Translation: CAJ64833.1.
    RefSeqiWP_011607260.1. NC_008278.1.
    YP_716348.1. NC_008278.1.

    Genome annotation databases

    GeneIDi4237482.
    KEGGifal:FRAAL6210.
    PATRICi21921492. VBIFraAln347_5688.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT573213 Genomic DNA. Translation: CAJ64833.1 .
    RefSeqi WP_011607260.1. NC_008278.1.
    YP_716348.1. NC_008278.1.

    3D structure databases

    ProteinModelPortali Q0RCJ1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 326424.FRAAL6210.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 4237482.
    KEGGi fal:FRAAL6210.
    PATRICi 21921492. VBIFraAln347_5688.

    Phylogenomic databases

    eggNOGi COG0495.
    HOGENOMi HOG000200748.
    KOi K01869.
    OMAi KGNPLES.
    OrthoDBi EOG63Z74X.

    Enzyme and pathway databases

    BioCyci FALN326424:GJ82-6107-MONOMER.

    Family and domain databases

    Gene3Di 1.10.730.10. 1 hit.
    3.40.50.620. 4 hits.
    3.90.740.10. 2 hits.
    HAMAPi MF_00049_B. Leu_tRNA_synth_B.
    InterProi IPR002302. Leu-tRNA-ligase.
    IPR025709. Leu_tRNA-synth_edit.
    IPR015413. Methionyl/Leucyl_tRNA_Synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    IPR009080. tRNAsynth_1a_anticodon-bd.
    IPR013155. V/L/I-tRNA-synth_anticodon-bd.
    IPR009008. Val/Leu/Ile-tRNA-synth_edit.
    [Graphical view ]
    PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
    Pfami PF08264. Anticodon_1. 1 hit.
    PF13603. tRNA-synt_1_2. 2 hits.
    PF09334. tRNA-synt_1g. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47323. SSF47323. 1 hit.
    SSF50677. SSF50677. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ACN14a.

    Entry informationi

    Entry nameiSYL_FRAAA
    AccessioniPrimary (citable) accession number: Q0RCJ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3