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Q0RAT5 (POTA_FRAAA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Spermidine/putrescine import ATP-binding protein PotA

EC=3.6.3.31
Gene names
Name:potA
Ordered Locus Names:FRAAL6832
OrganismFrankia alni (strain ACN14a) [Complete proteome] [HAMAP]
Taxonomic identifier326424 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesFrankineaeFrankiaceaeFrankia

Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system By similarity.

Catalytic activity

ATP + H2O + polyamine(Out) = ADP + phosphate + polyamine(In).

Subunit structure

The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD) Potential.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. [View classification]

Contains 1 ABC transporter domain.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentATP-binding cassette (ABC) transporter complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

putrescine-importing ATPase activity

Inferred from electronic annotation. Source: InterPro

spermidine-importing ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 465465Spermidine/putrescine import ATP-binding protein PotA
PRO_0000286219

Regions

Domain30 – 264235ABC transporter
Nucleotide binding66 – 738ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q0RAT5 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: F740084088D540CB

FASTA46549,827
        10         20         30         40         50         60 
MTATSGARTS DARTSGARTS DAGIGSPAAI ELVGVAKDYQ TRGRAVPAVS RVDLAIRPGE 

        70         80         90        100        110        120 
FFSLLGPSGC GKSTTLRMIA GFEEPTRGRI LLQGRDVTAV PPNRRDVNLV FQSYALFPHL 

       130        140        150        160        170        180 
DVAGNVAFGL RRRGVKGREL RERVGAMLDL VELSELADRR PRELSGGQQQ RVALARALVN 

       190        200        210        220        230        240 
RPAALLLDEP LGALDLKLRQ TMQIQLKAIQ REVGITFLYV THDQGEALTM SDRIAVMNGG 

       250        260        270        280        290        300 
RVEQLASPRD IYERPRTRFV AGFIGTSNLL RRTVRALDAA GPGGRPTVVL DAGTDERLSA 

       310        320        330        340        350        360 
PLHPPTGPLR AGDQVELTVR PEKIEMSVSR PDGPGCALRG RIVEVVYLGT YTTYTVATHG 

       370        380        390        400        410        420 
GTEITVFWQN STGAGNVAER GDEIWLSWLP EHSYVLPEPV ALPEPVALPG SVVPPETVNQ 

       430        440        450        460 
PDSVGPPDSI IPPHSVVAPD SVDPRETVVP AAGTSADPAA YRISH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CT573213 Genomic DNA. Translation: CAJ65455.1.
RefSeqYP_716959.1. NC_008278.1.

3D structure databases

ProteinModelPortalQ0RAT5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING326424.FRAAL6832.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4236983.
KEGGfal:FRAAL6832.
PATRIC21922617. VBIFraAln347_6241.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3842.
KOK11072.
OMAHISAEIS.
OrthoDBEOG6T7N3V.

Enzyme and pathway databases

BioCycFALN326424:GJ82-6731-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR017879. ABC_Sperm/Put_ATP-bd_PotA.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR008995. Mo/tungstate-bd_C_term_dom.
IPR027417. P-loop_NTPase.
IPR005893. Sp_pt_ABC_ATP-bd.
IPR013611. Transp-assoc_OB_typ2.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
PF08402. TOBE_2. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF50331. SSF50331. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR01187. potA. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51305. POTA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePOTA_FRAAA
AccessionPrimary (citable) accession number: Q0RAT5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families