Unreviewed, UniProtKB/TrEMBL Q0PW94 (Q0PW94_HUMAN)

Names and origin

Protein names

Submitted name:
    Intersectin 1 short form variant 5 EMBL ABG74698.1

Gene names

Name:

ITSN1 EMBL ABG74698.1

Organism

Homo sapiens (Human) EMBL ABG74698.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1215 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 5 SH3 domains. RuleBase RU003338V3

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3 Spearmint SPM013315
Gene Ontology (GO)
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0PW94-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 006C69DD67E5F153	FASTA	1,215	137,102
	10 20 30 40 50 60 MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 70 80 90 100 110 120 IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPPFGMGGI 130 140 150 160 170 180 ASMPPLTAVA PVPMGSIPVV GMSPTLVSSV PTAAVPPLAN GAPPVIQPLP AFAHPAATLP 190 200 210 220 230 240 KSSSFSRSGP GSQLNTKLQK AQSFDVASVP PVAEWAVPQS SRLKYRQLFN SHDKTMSGHL 250 260 270 280 290 300 TGPQARTILM QSSLPQAQLA SIWNLSDIDQ DGKLTAEEFI LAMHLIDVAM SGQPLPPVLP 310 320 330 340 350 360 PEYIPPSFRR VRSGSGISVI SSTSVDQRLP EEPVLEDEQQ QLEKKLPVTF EDKKRENFER 370 380 390 400 410 420 GNLELEKRRQ ALLEQQRKEQ ERLAQLERAE QERKERERQE QERKRQLELE KQLEKQRELE 430 440 450 460 470 480 RQREEERRKE IERREAAKRE LERQRQLEWE RNRRQELLNQ RNKEQEDIVV LKAKKKTLEF 490 500 510 520 530 540 ELEALNDKKH QLEGKLQDIR CRLTTQRQEI ESTNKSRELR IAEITHLQQQ LQESQQMLGR 550 560 570 580 590 600 LIPEKQILND QLKQVQQNSL HRDSLVTLKR ALEAKELARQ HLRDQLDEVE KETRSKLQEI 610 620 630 640 650 660 DIFNNQLKEL REIHNKQQLQ KQKSMEAERL KQKEQERKII ELEKQKEEAQ RRAQERDKQW 670 680 690 700 710 720 LEHVQQEDEH QRPRKLHEEE KLKREESVKK KDGEEKGKQE AQDKLGRLFH QHQEPAKPAV 730 740 750 760 770 780 QAPWSTAEKG PLTISAQENV KVVYYRALYP FESRSHDEIT IQPGDIVMVD ESQTGEPGWL 790 800 810 820 830 840 GGELKGKTGW FPANYAEKIP ENEVPAPVKP VTDSTSAPAP KLALRETPAP LAVTSSEPST 850 860 870 880 890 900 TPNNWADFSS TWPTSTNEKP ETDNWDAWAA QPSLTVPSAG QLRQRSAFTP ATATGSSPSP 910 920 930 940 950 960 VLGQGEKVEG LQAQALYPWR AKKDNHLNFN KNDVITVLEQ QDMWWFGEVQ GQKGWFPKSY 970 980 990 1000 1010 1020 VKLISGPIRK STSMDSGSSE SPASLKRVAS PAAKPVVSGE EFIAMYTYES SEQGDLTFQQ 1030 1040 1050 1060 1070 1080 GDVILVTKKD GDWWTGTVGD KAGVFPSNYV RLKDSEGSGT AGKTGSLGKK PEIAQVIASY 1090 1100 1110 1120 1130 1140 TATGPEQLTL APGQLILIRK KNPGGWWEGE LQARGKKRQI GWFPANYVKL LNPGTSKITP 1150 1160 1170 1180 1190 1200 TEPPKSTALA AVCQVIGMYD YTAQNDDELA FNKGQIINVL NKEDPDWWKG EVNGQVGLFP 1210 SNYVKLTTDM DPSQQ

References

[1]	"Isolation and characterization of the novel complete coding sequence isoforms of intersectin 1." Kropyvko S., Tsyba L., Skrypkina I., Rynditch A. Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL ABG74698.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	DQ679757 mRNA. Translation: ABG74698.1.
UniGene	Hs.160324
3D structure databases
SMR	Q0PW94. Positions 908-966.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000205726. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:6183. ITSN1.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q0PW94.
Gene expression databases
ArrayExpress	Q0PW94.
Family and domain databases
InterPro	IPR011992. EF-Hand_type. IPR002048. EF_hand_Ca_bd. IPR000261. EPS15_homology. IPR001452. SH3_domain. IPR013315. Spectrin_alpha_SH3. [Graphical view]
Gene3D	G3DSA:1.10.238.10. EF-Hand_type. 2 hits.
Pfam	PF00036. efhand. 2 hits. PF00018. SH3_1. 5 hits. [Graphical view]
PRINTS	PR00452. SH3DOMAIN. PR01887. SPECTRNALPHA.
ProDom	PD000066. SH3. 5 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00054. EFh. 2 hits. SM00027. EH. 2 hits. SM00326. SH3. 5 hits. [Graphical view]
PROSITE	PS00018. EF_HAND_1. 2 hits. PS50222. EF_HAND_2. 2 hits. PS50031. EH. 2 hits. PS50002. SH3. 5 hits. [Graphical view]

Entry information

Entry name

Q0PW94_HUMAN

Accession

Primary (citable) accession number: Q0PW94

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	November 25, 2008
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)