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Q0PRL4

- Q0PRL4_HUMAN

UniProt

Q0PRL4 - Q0PRL4_HUMAN

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Protein
Submitted name:

Forkhead box P2 variant 3

Gene
FOXP2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box P2 variant 3Imported
Submitted name:
Forkhead box protein P2Imported
Gene namesi
Name:FOXP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:13875. FOXP2.

Structurei

3D structure databases

ProteinModelPortaliQ0PRL4.
SMRiQ0PRL4. Positions 259-317, 329-399.

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000092089.
HOVERGENiHBG051657.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0PRL4-1 [UniParc]FASTAAdd to Basket

« Hide

MMTPQVITPQ QMQQILQQQV LSPQQLQALL QQQQAVMLQQ QQLQEFYKKQ    50
QEQLHLQLLQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQH 100
PGKQAKEQQQ QQQQQQQLAA QQLVFQQQLL QMQQLQQQQH LLSLQRQGLI 150
SIPPGQAALP VQSLPQAGLS PAEIQQLWKE VTGVHSMEDN GIKHGGLDLT 200
TNNSSSTTSS NTSKASPPIT HHSIVNGQSS VLSARRDSSS HEETGASHTL 250
YGHGVCKWPG CESICEDFGQ FLKHLNNEHA LDDRSTAQCR VQMQVVQQLE 300
IQLSKERERL QAMMTHLHMR PSEPKPSPKP AIMESSDRQL TLNEIYSWFT 350
RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS 400
QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS 450
GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC 500
PMSLVTTANH SPELEDDREI EEEPLSEDLE 530
Length:530
Mass (Da):59,922
Last modified:September 5, 2006 - v1
Checksum:i667D6EFD3F3312F3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
DQ778626 mRNA. Translation: ABG77460.1.
UniGeneiHs.282787.

Genome annotation databases

EnsembliENST00000393491; ENSP00000377130; ENSG00000128573.
UCSCiuc010ljz.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
DQ778626 mRNA. Translation: ABG77460.1 .
UniGenei Hs.282787.

3D structure databases

ProteinModelPortali Q0PRL4.
SMRi Q0PRL4. Positions 259-317, 329-399.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000393491 ; ENSP00000377130 ; ENSG00000128573 .
UCSCi uc010ljz.2. human.

Organism-specific databases

HGNCi HGNC:13875. FOXP2.
GenAtlasi Search...

Phylogenomic databases

HOGENOMi HOG000092089.
HOVERGENi HBG051657.

Miscellaneous databases

ChiTaRSi FOXP2. human.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
PROSITEi PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Lin L., Nong W., Zhou G., Ke R., Shen C., Liang M., Tang Z., Huang B., Li H., Yang S.
    Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ0PRL4_HUMAN
AccessioniPrimary (citable) accession number: Q0PRL4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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