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Protein
Submitted name:

Forkhead box P2 variant 3

Gene

FOXP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi331 – 392Fork-headPROSITE-ProRule annotationAdd BLAST62

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscriptionSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box P2 variant 3Imported
Submitted name:
Forkhead box protein P2Imported
Gene namesi
Name:FOXP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000128573.23
HGNCiHGNC:13875 FOXP2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000128573

PTM / Processingi

Proteomic databases

MaxQBiQ0PRL4

Expressioni

Gene expression databases

BgeeiENSG00000128573

Structurei

3D structure databases

SMRiQ0PRL4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini331 – 392Fork-headInterPro annotationAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili49 – 99Sequence analysisAdd BLAST51
Coiled coili296 – 316Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4385 Eukaryota
COG5025 LUCA
GeneTreeiENSGT00920000148947
HOGENOMiHOG000092089
HOVERGENiHBG051657

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR001766 Fork_head_dom
IPR032354 FOXP-CC
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00250 Forkhead, 1 hit
PF16159 FOXP-CC, 1 hit
PRINTSiPR00053 FORKHEAD
SMARTiView protein in SMART
SM00339 FH, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS00658 FORK_HEAD_2, 1 hit
PS50039 FORK_HEAD_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q0PRL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMTPQVITPQ QMQQILQQQV LSPQQLQALL QQQQAVMLQQ QQLQEFYKKQ
60 70 80 90 100
QEQLHLQLLQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQH
110 120 130 140 150
PGKQAKEQQQ QQQQQQQLAA QQLVFQQQLL QMQQLQQQQH LLSLQRQGLI
160 170 180 190 200
SIPPGQAALP VQSLPQAGLS PAEIQQLWKE VTGVHSMEDN GIKHGGLDLT
210 220 230 240 250
TNNSSSTTSS NTSKASPPIT HHSIVNGQSS VLSARRDSSS HEETGASHTL
260 270 280 290 300
YGHGVCKWPG CESICEDFGQ FLKHLNNEHA LDDRSTAQCR VQMQVVQQLE
310 320 330 340 350
IQLSKERERL QAMMTHLHMR PSEPKPSPKP AIMESSDRQL TLNEIYSWFT
360 370 380 390 400
RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS
410 420 430 440 450
QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS
460 470 480 490 500
GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC
510 520 530
PMSLVTTANH SPELEDDREI EEEPLSEDLE
Length:530
Mass (Da):59,922
Last modified:September 5, 2006 - v1
Checksum:i667D6EFD3F3312F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073626 Genomic DNA No translation available.
AC074000 Genomic DNA No translation available.
AC092148 Genomic DNA No translation available.
AC092606 Genomic DNA No translation available.
KF458557 Genomic DNA No translation available.
KF458560 Genomic DNA No translation available.
KF458565 Genomic DNA No translation available.
DQ778626 mRNA Translation: ABG77460.1
UniGeneiHs.282787

Genome annotation databases

EnsembliENST00000393491; ENSP00000377130; ENSG00000128573
UCSCiuc064hfd.1 human

Similar proteinsi

Entry informationi

Entry nameiQ0PRL4_HUMAN
AccessioniPrimary (citable) accession number: Q0PRL4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: June 20, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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