Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0PRL4

- Q0PRL4_HUMAN

UniProt

Q0PRL4 - Q0PRL4_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Forkhead box P2 variant 3

Gene

FOXP2

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Forkhead box P2 variant 3Imported
Submitted name:
Forkhead box protein P2Imported
Gene namesi
Name:FOXP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:13875. FOXP2.

Expressioni

Gene expression databases

ExpressionAtlasiQ0PRL4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ0PRL4.
SMRiQ0PRL4. Positions 259-317, 329-399.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains fork-head DNA-binding domain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00750000117475.
HOGENOMiHOG000092089.
HOVERGENiHBG051657.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view]
PfamiPF00250. Fork_head. 1 hit.
[Graphical view]
PRINTSiPR00053. FORKHEAD.
SMARTiSM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view]
PROSITEiPS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0PRL4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMTPQVITPQ QMQQILQQQV LSPQQLQALL QQQQAVMLQQ QQLQEFYKKQ
60 70 80 90 100
QEQLHLQLLQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQH
110 120 130 140 150
PGKQAKEQQQ QQQQQQQLAA QQLVFQQQLL QMQQLQQQQH LLSLQRQGLI
160 170 180 190 200
SIPPGQAALP VQSLPQAGLS PAEIQQLWKE VTGVHSMEDN GIKHGGLDLT
210 220 230 240 250
TNNSSSTTSS NTSKASPPIT HHSIVNGQSS VLSARRDSSS HEETGASHTL
260 270 280 290 300
YGHGVCKWPG CESICEDFGQ FLKHLNNEHA LDDRSTAQCR VQMQVVQQLE
310 320 330 340 350
IQLSKERERL QAMMTHLHMR PSEPKPSPKP AIMESSDRQL TLNEIYSWFT
360 370 380 390 400
RTFAYFRRNA ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEVEYQKRRS
410 420 430 440 450
QKITGSPTLV KNIPTSLGYG AALNASLQAA LAESSLPLLS NPGLINNASS
460 470 480 490 500
GLLQAVHEDL NGSLDHIDSN GNSSPGCSPQ PHIHSIHVKE EPVIAEDEDC
510 520 530
PMSLVTTANH SPELEDDREI EEEPLSEDLE
Length:530
Mass (Da):59,922
Last modified:September 5, 2006 - v1
Checksum:i667D6EFD3F3312F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
KF458557 Genomic DNA. No translation available.
KF458560 Genomic DNA. No translation available.
KF458565 Genomic DNA. No translation available.
DQ778626 mRNA. Translation: ABG77460.1.
UniGeneiHs.282787.

Genome annotation databases

EnsembliENST00000393491; ENSP00000377130; ENSG00000128573.
UCSCiuc010ljz.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003992 Genomic DNA. No translation available.
AC020606 Genomic DNA. No translation available.
AC073626 Genomic DNA. No translation available.
AC074000 Genomic DNA. No translation available.
AC092148 Genomic DNA. No translation available.
AC092606 Genomic DNA. No translation available.
KF458557 Genomic DNA. No translation available.
KF458560 Genomic DNA. No translation available.
KF458565 Genomic DNA. No translation available.
DQ778626 mRNA. Translation: ABG77460.1 .
UniGenei Hs.282787.

3D structure databases

ProteinModelPortali Q0PRL4.
SMRi Q0PRL4. Positions 259-317, 329-399.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000393491 ; ENSP00000377130 ; ENSG00000128573 .
UCSCi uc010ljz.2. human.

Organism-specific databases

HGNCi HGNC:13875. FOXP2.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00750000117475.
HOGENOMi HOG000092089.
HOVERGENi HBG051657.

Miscellaneous databases

ChiTaRSi FOXP2. human.

Gene expression databases

ExpressionAtlasi Q0PRL4. baseline and differential.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
IPR015880. Znf_C2H2-like.
[Graphical view ]
Pfami PF00250. Fork_head. 1 hit.
[Graphical view ]
PRINTSi PR00053. FORKHEAD.
SMARTi SM00339. FH. 1 hit.
SM00355. ZnF_C2H2. 1 hit.
[Graphical view ]
PROSITEi PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of human chromosome 7."
    Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
    , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
    Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Lin L., Nong W., Zhou G., Ke R., Shen C., Liang M., Tang Z., Huang B., Li H., Yang S.
    Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ0PRL4_HUMAN
AccessioniPrimary (citable) accession number: Q0PRL4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3