ID   Q0PMN1_MOUSE            Unreviewed;       211 AA.
AC   Q0PMN1;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   03-MAR-2009, entry version 20.
DE   SubName: Full=Interleukin-6;
GN   Name=Il6;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;
OC   Muroidea; Muridae; Murinae; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BALB/c;
RA   Liu Y.-L., Fan Y.-H., Chiou S.-H.;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; DQ788722; ABG81953.1; -; mRNA.
DR   IPI; IPI00133702; -.
DR   UniGene; Mm.1019; -.
DR   Ensembl; ENSMUSG00000025746; Mus musculus.
DR   MGI; MGI:96559; Il6.
DR   HOVERGEN; Q0PMN1; -.
DR   ArrayExpress; Q0PMN1; -.
DR   Bgee; Q0PMN1; -.
DR   GO; GO:0009897; C:external side of plasma membrane; IDA:MGI.
DR   GO; GO:0005615; C:extracellular space; IDA:MGI.
DR   GO; GO:0005125; F:cytokine activity; IDA:MGI.
DR   GO; GO:0005138; F:interleukin-6 receptor binding; IEA:InterPro.
DR   GO; GO:0042832; P:defense response to protozoan; IMP:MGI.
DR   GO; GO:0046716; P:muscle maintenance; IGI:MGI.
DR   GO; GO:0045079; P:negative regulation of chemokine biosynthet...; IDA:MGI.
DR   GO; GO:0046888; P:negative regulation of hormone secretion; IDA:MGI.
DR   GO; GO:0001781; P:neutrophil apoptosis; IDA:MGI.
DR   GO; GO:0050679; P:positive regulation of epithelial cell prol...; IDA:MGI.
DR   GO; GO:0045630; P:positive regulation of T-helper 2 cell diff...; IDA:MGI.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-d...; IDA:MGI.
DR   GO; GO:0007435; P:salivary gland morphogenesis; IDA:MGI.
DR   InterPro; IPR012351; 4_helix_cytokine_core.
DR   InterPro; IPR003573; IL6_MGF_GCSF.
DR   InterPro; IPR003574; Interleukin_6.
DR   Gene3D; G3DSA:1.20.1250.10; 4_helix_cytokine_core; 1.
DR   PANTHER; PTHR11457; Interleukin_6; 1.
DR   Pfam; PF00489; IL6; 1.
DR   PIRSF; PIRSF001935; IL6_MGF_GCSF; 1.
DR   PRINTS; PR00433; IL6GCSFMGF.
DR   PRINTS; PR00434; INTERLEUKIN6.
DR   SMART; SM00126; IL6; 1.
DR   PROSITE; PS00254; INTERLEUKIN_6; 1.
PE   2: Evidence at transcript level;
SQ   SEQUENCE   211 AA;  24368 MW;  BBB466B69E86787A CRC64;
     MKFLSARDFH PVAFLGLMLV TTTAFPTSQV RRGDFTEDTT PNRPVYTTSQ VGGLITHVLW
     EIVEMRKELC NGNSDCMNND DALAENNLKL PEIQRNDGCY QTGYNQEICL LKISSGLLEY
     HSYLEYMKNN LKDNKKDKAR VLQRDTETLI HIFNQEVKDL HKIVLPTPIS NALLTDKLES
     QKEWLRTKTI QFILKSLEEF PKVTLRSTRQ T
//