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Q0PCR5 (Q0PCR5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Cacna1c MGI 103013
Synonyms:CaV1.2-b EMBL BAF03166.1
OrganismMus musculus (Mouse) EMBL BAF03166.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length138 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Ontologies

Keywords
   Biological processCalcium transport
Ion transport
Transport
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU003378
   LigandCalcium
   Molecular functionCalcium channel RuleBase RU003808
Ion channel
Voltage-gated channel RuleBase RU003808
Gene Ontology (GO)
   Biological_processadult walking behavior

Inferred from genetic interaction PubMed 9882694. Source: MGI

calcium ion import

Inferred from Biological aspect of Ancestor. Source: RefGenome

calcium ion transport

Inferred from direct assay PubMed 7635187. Source: MGI

calcium ion-dependent exocytosis

Inferred from mutant phenotype PubMed 12881419. Source: MGI

cellular calcium ion homeostasis

Inferred from mutant phenotype PubMed 15132976. Source: MGI

glucose homeostasis

Inferred from mutant phenotype PubMed 12881419. Source: MGI

growth hormone secretion

Inferred from direct assay PubMed 1385406. Source: MGI

insulin secretion

Inferred from mutant phenotype PubMed 12881419. Source: MGI

membrane depolarization during action potential

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of cytosolic calcium ion concentration

Inferred from electronic annotation. Source: Ensembl

regulation of blood pressure

Inferred from mutant phenotype PubMed 14609949. Source: MGI

regulation of organ growth

Inferred from mutant phenotype PubMed 15132976. Source: MGI

regulation of vasoconstriction

Inferred from mutant phenotype PubMed 14609949. Source: MGI

smooth muscle contraction

Inferred from mutant phenotype PubMed 16636102. Source: MGI

smooth muscle contraction involved in micturition

Inferred from mutant phenotype PubMed 15132976. Source: MGI

synaptic transmission

Inferred from mutant phenotype PubMed 16251435. Source: MGI

visual learning

Inferred from mutant phenotype PubMed 16251435. Source: MGI

   Cellular_componentT-tubule

Traceable author statement PubMed 11784029. Source: MGI

Z disc

Inferred from direct assay PubMed 19383796. Source: MGI

caveolar macromolecular signaling complex

Inferred from direct assay PubMed 16648270. Source: MGI

dendritic shaft

Inferred from direct assay PubMed 15090038. Source: MGI

membrane

Inferred from direct assay PubMed 15132976. Source: MGI

neuronal cell body

Inferred from direct assay PubMed 15090038. Source: MGI

plasma membrane

Inferred from direct assay PubMed 15090038PubMed 7598723. Source: MGI

postsynaptic density

Inferred from electronic annotation. Source: Ensembl

voltage-gated calcium channel complex

Traceable author statement PubMed 11296258. Source: MGI

   Molecular_functionhigh voltage-gated calcium channel activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

protein binding

Inferred from physical interaction Ref.1. Source: MGI

voltage-gated calcium channel activity

Inferred from direct assay PubMed 1385406PubMed 16267232PubMed 7635187PubMed 7814415. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAF03166.1
Non-terminal residue1381 EMBL BAF03166.1

Sequences

Sequence LengthMass (Da)Tools
Q0PCR5 [UniParc].

Last modified September 19, 2006. Version 1.
Checksum: C9528C40B999AF89

FASTA13815,927
        10         20         30         40         50         60 
TMEGWTDVLY WVNDAVGRDW PWIYFVTLII IGSFFVLNLV LGVLSGEFSK EREKAKARGD 

        70         80         90        100        110        120 
FQKLREKQQL EEDLKGYLDW ITQAEDIDPE NEDEGMDEDK PRNRGAPAGL HDQKKGKFAW 

       130 
FSHSTETHVS MPTSETES 

« Hide

References

[1]"Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit."
Murakami M., Ohba T., Takahashi Y., Watanabe H., Miyoshi I., Nakayama S., Ono K., Ito H., Iijima T.
J. Mol. Cell. Cardiol. 41:115-125(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Aorta EMBL BAF03166.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB259050 mRNA. Translation: BAF03166.1.
UniGeneMm.41628.
Mm.436656.

3D structure databases

ProteinModelPortalQ0PCR5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:103013. Cacna1c.

Gene expression databases

ArrayExpressQ0PCR5.
BgeeQ0PCR5.
GenevestigatorQ0PCR5.

Family and domain databases

InterProIPR005821. Ion_trans_dom.
IPR002077. VDCCAlpha1.
[Graphical view]
PfamPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSPR00167. CACHANNEL.
ProtoNetSearch...

Other

ChiTaRSCACNA1C. mouse.
SOURCESearch...

Entry information

Entry nameQ0PCR5_MOUSE
AccessionPrimary (citable) accession number: Q0PCR5
Entry history
Integrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)