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Protein
Submitted name:

Voltage-dependent calcium channel splice variant 1.2-b

Gene

Cacna1c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Calcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation

Keywords - Biological processi

Calcium transport, Ion transport, Transport

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Submitted name:
Voltage-dependent calcium channel splice variant 1.2-bImported
Gene namesi
Name:Cacna1cImported
Synonyms:CaV1.2-bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:103013. Cacna1c.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 44HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ0PCR5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000051331.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108413.

Structurei

3D structure databases

ProteinModelPortaliQ0PCR5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 55Ion_transInterPro annotationAdd BLAST55

Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2301. Eukaryota.
ENOG410XNP6. LUCA.

Family and domain databases

InterProiIPR005821. Ion_trans_dom.
IPR005451. VDCC_L_a1csu.
IPR002077. VDCCAlpha1.
[Graphical view]
PANTHERiPTHR10037:SF188. PTHR10037:SF188. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00167. CACHANNEL.

Sequencei

Sequence statusi: Fragment.

Q0PCR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
TMEGWTDVLY WVNDAVGRDW PWIYFVTLII IGSFFVLNLV LGVLSGEFSK
60 70 80 90 100
EREKAKARGD FQKLREKQQL EEDLKGYLDW ITQAEDIDPE NEDEGMDEDK
110 120 130
PRNRGAPAGL HDQKKGKFAW FSHSTETHVS MPTSETES
Length:138
Mass (Da):15,927
Last modified:September 19, 2006 - v1
Checksum:iC9528C40B999AF89
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei138Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB259050 mRNA. Translation: BAF03166.1.
UniGeneiMm.41628.
Mm.436656.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB259050 mRNA. Translation: BAF03166.1.
UniGeneiMm.41628.
Mm.436656.

3D structure databases

ProteinModelPortaliQ0PCR5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108413.

Proteomic databases

PaxDbiQ0PCR5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:103013. Cacna1c.

Phylogenomic databases

eggNOGiKOG2301. Eukaryota.
ENOG410XNP6. LUCA.

Miscellaneous databases

ChiTaRSiCacna1c. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000051331.

Family and domain databases

InterProiIPR005821. Ion_trans_dom.
IPR005451. VDCC_L_a1csu.
IPR002077. VDCCAlpha1.
[Graphical view]
PANTHERiPTHR10037:SF188. PTHR10037:SF188. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00167. CACHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ0PCR5_MOUSE
AccessioniPrimary (citable) accession number: Q0PCR5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.