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Protein

Aspartate ammonia-lyase

Gene

aspA

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-83-MONOMER.
BRENDAi4.3.1.1. 1087.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyaseUniRule annotation (EC:4.3.1.1UniRule annotation)
Short name:
AspartaseUniRule annotation
Gene namesi
Name:aspAImported
Ordered Locus Names:Cj0087Imported
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)Imported
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiQ0PC50.

Interactioni

Protein-protein interaction databases

IntActiQ0PC50. 49 interactions.
STRINGi192222.Cj0087.

Structurei

3D structure databases

ProteinModelPortaliQ0PC50.
SMRiQ0PC50. Positions 2-455.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 342332Lyase_1InterPro annotationAdd
BLAST
Domaini408 – 46053FumaraseC_CInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili157 – 18125Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0PC50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTRKEHDFI GELEISDEVY YGVQTFRAVE NFDISHDRLK DFPRFVRALA
60 70 80 90 100
RVKKAAAMAN HELGLLDKNI QDAIIKACDK ILEGGYYDQF VVDMIQGGAG
110 120 130 140 150
TSTNMNANEV IANIGLELMG HKKGEYQYLH PNDHVNLSQS TNDAYPTALH
160 170 180 190 200
LALHDYLSDL AKAMEHLKKA YERKAEEFKD VLKMGRTQLQ DAVPMTLGRE
210 220 230 240 250
FKTFAVMIGE DIQRVLEARK LILEINLGGT AIGTGINSHP DYPKVVERKI
260 270 280 290 300
REVTGFEYTV AEDLIEATQD TGAYVQISGV LKRVATKLSK VCNDLRLLSS
310 320 330 340 350
GPKCGLNEIN LPKMQPGSSI MPGKVNPVIP EVVNQVCYFV IGADVTVTFA
360 370 380 390 400
CEGGQLQLNV FEPVVAYSLF NSVVMLEKAM YTLADKCIDG ITANEKICSD
410 420 430 440 450
FVYNSVGIVT ALNPYIGYEN SASIAKEAMN TGKRVADIAL ERGLLSKEQI
460
DEILTPSNML NPHMEAKK
Length:468
Mass (Da):51,765
Last modified:September 19, 2006 - v1
Checksum:iB5A16408C53F2C7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34258.1.
PIRiG81424.
RefSeqiWP_002851742.1. NC_002163.1.
YP_002343547.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34258; CAL34258; Cj0087.
GeneIDi904412.
KEGGicje:Cj0087.
PATRICi20057101. VBICamJej33762_0085.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34258.1.
PIRiG81424.
RefSeqiWP_002851742.1. NC_002163.1.
YP_002343547.1. NC_002163.1.

3D structure databases

ProteinModelPortaliQ0PC50.
SMRiQ0PC50. Positions 2-455.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ0PC50. 49 interactions.
STRINGi192222.Cj0087.

Proteomic databases

PaxDbiQ0PC50.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL34258; CAL34258; Cj0087.
GeneIDi904412.
KEGGicje:Cj0087.
PATRICi20057101. VBICamJej33762_0085.

Phylogenomic databases

eggNOGiENOG4108IJ0. Bacteria.
COG1027. LUCA.
HOGENOMiHOG000061737.
KOiK01744.
OMAiEICENYV.

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-83-MONOMER.
BRENDAi4.3.1.1. 1087.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR004708. ApsA.
IPR024083. Fumarase/histidase_N.
IPR018951. Fumarase_C_C.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10415. FumaraseC_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00839. aspA. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ0PC50_CAMJE
AccessioniPrimary (citable) accession number: Q0PC50
Entry historyi
Integrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: September 7, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.