Unreviewed, UniProtKB/TrEMBL Q0PBB8 (Q0PBB8_CAMJE)

Names and origin

Protein names

Recommended name:
    Pyruvate kinase RuleBase RU000504V4
    EC=2.7.1.40

Gene names

Name:	pyk EMBL CAL34542.1
Ordered Locus Names:	Cj0392c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	ATP + pyruvate = ADP + phosphoenolpyruvate. RuleBase RU000504V4
Cofactor	Divalent metal cations By similarity. RuleBase RU000504V4
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5. RuleBase RU000504V4
Sequence similarities	Belongs to the pyruvate kinase family. RuleBase RU000504V4

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU000504V4
Ligand	Magnesium RuleBase RU000504V4 Pyruvate
Molecular function	Kinase RuleBase RU000504V4 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro potassium ion binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct pyruvate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
fliH	Q0PBI9	1	EBI-1191902,EBI-1191439
fliM	Q0PC73	1	EBI-1191902,EBI-1191095
fliN	O32370	1	EBI-1191902,EBI-1191320
fliY	Q0PC74	1	EBI-1191902,EBI-1191111

Sequences

	Sequence		Length	Mass (Da)
	Q0PBB8-1 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: 7EF4B1E1DC352D7C	FASTA	480	53,858
	10 20 30 40 50 60 MLKKTKIVAT VGPASEKEEI LRQMIINGVN VFRLNFSHGT HEYHKKNLDT IRRVAKELHT 70 80 90 100 110 120 RIGILQDISG PKIRTGELKE PFELKKGDRL DFYRETILGE KIAQNHYKIS INQKSILDML 130 140 150 160 170 180 KIDEYIYLYD GSIRAKVVNI DNQKIETIIE NDGFLNSNKG INFPNTKINI DVITQKDKND 190 200 210 220 230 240 LLWGIKNEVD FLAISFVQNA HDIDEVREIL AQNNAKISIF AKIEKFDAVE NIDEIIKSSD 250 260 270 280 290 300 GIMVARGDLG IEVPYYKVPN IQKEIIQKAN NASKPVITAT QMLFSLAKSK TATRAEISDV 310 320 330 340 350 360 ANAVLDGTDA VMLSEESAVG IDPANAVDIM CQTIIETEKR YPYNKFNDFN DLDNTDKIMR 370 380 390 400 410 420 SSAHLATDLN ADAIFSLTSS GKSAIKIARY RPNIEIIAVG HSEKTLNSLS IVWGVNPAIL 430 440 450 460 470 480 VNKSNELTEL LKDSVRSSVE KGFMDEDKCY LLTAGFPTGV EGTSNLIRIL NKEQIAYYLQ

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL34542.1.
PIR	F81382.
RefSeq	YP_002343829.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	Q0PBB8. 157 interactions.
Genome annotation databases
GeneID	904715.
GenomeReviews	Gene locus Cj0392c in contig AL111168_GR.
KEGG	cje:Cj0392c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0PBB8.
OMA	Q0PBB8. RERPKAP.
Family and domain databases
InterPro	IPR018087. Glyco_hydro_5_CS. IPR001697. Pyr_Knase. IPR015813. Pyrv/PenolPyrv_Kinase_cat. IPR015794. Pyrv_Knase_a/b. IPR015793. Pyrv_Knase_brl. [Graphical view]
Gene3D	G3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PANTHER	PTHR11817. Pyruvate_kinase. 1 hit.
Pfam	PF00224. PK. 1 hit. PF02887. PK_C. 1 hit. [Graphical view]
PRINTS	PR01050. PYRUVTKNASE.
ProDom	PD001009. Pyruvate_kinase. 2 hits. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01064. pyruv_kin. 1 hit.
PROSITE	PS00659. GLYCOSYL_HYDROL_F5. 1 hit. Uncertain. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0PBB8_CAMJE

Accession

Primary (citable) accession number: Q0PBB8

Entry history

Integrated into UniProtKB/TrEMBL:	September 19, 2006
Last sequence update:	September 19, 2006
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)