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Q0PAY5

- Q0PAY5_CAMJE

UniProt

Q0PAY5 - Q0PAY5_CAMJE

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Protein
Submitted name:

Isocitrate dehydrogenase

Gene
icd, Cj0531
Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421Substrate By similarityUniRule annotation
Sitei252 – 2521Critical for catalysis By similarity
Metal bindingi345 – 3451Magnesium or manganese By similarityUniRule annotation
Sitei415 – 4151Critical for catalysis By similarityUniRule annotation
Binding sitei538 – 5381Substrate By similarityUniRule annotation
Metal bindingi539 – 5391Magnesium or manganese By similarityUniRule annotation
Metal bindingi543 – 5431Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-515-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:Cj0531Imported
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)Imported
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799: Chromosome

Interactioni

Protein-protein interaction databases

IntActiQ0PAY5. 7 interactions.
STRINGi192222.Cj0531.

Structurei

3D structure databases

ProteinModelPortaliQ0PAY5.
SMRiQ0PAY5. Positions 2-731.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni129 – 1368Substrate binding By similarityUniRule annotation

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0PAY5-1 [UniParc]FASTAAdd to Basket

« Hide

MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
IENSSKKDEI LKKYSEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
LQASLEFYAN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
Length:734
Mass (Da):82,331
Last modified:September 19, 2006 - v1
Checksum:i39E62BC90977B41B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL34677.1.
PIRiC81399.
RefSeqiYP_002343962.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34677; CAL34677; Cj0531.
GeneIDi904859.
KEGGicje:Cj0531.
PATRICi20058002. VBICamJej33762_0523.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL111168 Genomic DNA. Translation: CAL34677.1 .
PIRi C81399.
RefSeqi YP_002343962.1. NC_002163.1.

3D structure databases

ProteinModelPortali Q0PAY5.
SMRi Q0PAY5. Positions 2-731.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q0PAY5. 7 interactions.
STRINGi 192222.Cj0531.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL34677 ; CAL34677 ; Cj0531 .
GeneIDi 904859.
KEGGi cje:Cj0531.
PATRICi 20058002. VBICamJej33762_0523.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci CJEJ192222:GJTS-515-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168Imported.

Entry informationi

Entry nameiQ0PAY5_CAMJE
AccessioniPrimary (citable) accession number: Q0PAY5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: July 9, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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