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Q0PAY5

- Q0PAY5_CAMJE

UniProt

Q0PAY5 - Q0PAY5_CAMJE

Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (19 Sep 2006)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei142 – 1421SubstrateUniRule annotation
    Sitei252 – 2521Critical for catalysisUniRule annotation
    Metal bindingi345 – 3451Magnesium or manganese
    Sitei415 – 4151Critical for catalysisUniRule annotation
    Binding sitei538 – 5381SubstrateUniRule annotation
    Metal bindingi539 – 5391Magnesium or manganese
    Metal bindingi543 – 5431Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciCJEJ192222:GJTS-515-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:Cj0531Imported
    OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)Imported
    Taxonomic identifieri192222 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000000799: Chromosome

    Interactioni

    Protein-protein interaction databases

    IntActiQ0PAY5. 7 interactions.
    STRINGi192222.Cj0531.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0PAY5.
    SMRiQ0PAY5. Positions 2-731.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni129 – 1368Substrate bindingUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0PAY5-1 [UniParc]FASTAAdd to Basket

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    MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
    EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
    GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
    YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
    DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
    LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
    IENSSKKDEI LKKYSEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
    MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
    SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
    RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
    KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
    GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
    LQASLEFYAN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
    HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
    VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
    Length:734
    Mass (Da):82,331
    Last modified:September 19, 2006 - v1
    Checksum:i39E62BC90977B41B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL111168 Genomic DNA. Translation: CAL34677.1.
    PIRiC81399.
    RefSeqiYP_002343962.1. NC_002163.1.

    Genome annotation databases

    EnsemblBacteriaiCAL34677; CAL34677; Cj0531.
    GeneIDi904859.
    KEGGicje:Cj0531.
    PATRICi20058002. VBICamJej33762_0523.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL111168 Genomic DNA. Translation: CAL34677.1 .
    PIRi C81399.
    RefSeqi YP_002343962.1. NC_002163.1.

    3D structure databases

    ProteinModelPortali Q0PAY5.
    SMRi Q0PAY5. Positions 2-731.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q0PAY5. 7 interactions.
    STRINGi 192222.Cj0531.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAL34677 ; CAL34677 ; Cj0531 .
    GeneIDi 904859.
    KEGGi cje:Cj0531.
    PATRICi 20058002. VBICamJej33762_0523.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci CJEJ192222:GJTS-515-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NCTC 11168Imported.

    Entry informationi

    Entry nameiQ0PAY5_CAMJE
    AccessioniPrimary (citable) accession number: Q0PAY5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 19, 2006
    Last sequence update: September 19, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3