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Q0PAY5

- Q0PAY5_CAMJE

UniProt

Q0PAY5 - Q0PAY5_CAMJE

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Protein
Submitted name:

Isocitrate dehydrogenase

Gene

icd

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421SubstrateUniRule annotation
Sitei252 – 2521Critical for catalysisUniRule annotation
Sitei415 – 4151Critical for catalysisUniRule annotation
Binding sitei538 – 5381SubstrateUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-515-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenaseImported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:Cj0531Imported
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)Imported
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000000799: Chromosome

Interactioni

Protein-protein interaction databases

IntActiQ0PAY5. 7 interactions.
STRINGi192222.Cj0531.

Structurei

3D structure databases

ProteinModelPortaliQ0PAY5.
SMRiQ0PAY5. Positions 2-731.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni129 – 1368Substrate bindingUniRule annotation

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiEEQRIGD.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0PAY5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS
60 70 80 90 100
EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK
110 120 130 140 150
GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD
160 170 180 190 200
YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV
210 220 230 240 250
DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH
260 270 280 290 300
LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK
310 320 330 340 350
IENSSKKDEI LKKYSEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA
360 370 380 390 400
MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG
410 420 430 440 450
SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY
460 470 480 490 500
RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL
510 520 530 540 550
KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL
560 570 580 590 600
GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA
610 620 630 640 650
LQASLEFYAN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS
660 670 680 690 700
HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK
710 720 730
VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR
Length:734
Mass (Da):82,331
Last modified:September 19, 2006 - v1
Checksum:i39E62BC90977B41B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34677.1.
PIRiC81399.
RefSeqiYP_002343962.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34677; CAL34677; Cj0531.
GeneIDi904859.
KEGGicje:Cj0531.
PATRICi20058002. VBICamJej33762_0523.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34677.1 .
PIRi C81399.
RefSeqi YP_002343962.1. NC_002163.1.

3D structure databases

ProteinModelPortali Q0PAY5.
SMRi Q0PAY5. Positions 2-731.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q0PAY5. 7 interactions.
STRINGi 192222.Cj0531.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAL34677 ; CAL34677 ; Cj0531 .
GeneIDi 904859.
KEGGi cje:Cj0531.
PATRICi 20058002. VBICamJej33762_0523.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.
OMAi EEQRIGD.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci CJEJ192222:GJTS-515-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NCTC 11168Imported.

Entry informationi

Entry nameiQ0PAY5_CAMJE
AccessioniPrimary (citable) accession number: Q0PAY5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: November 26, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3