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Protein

Potassium-transporting ATPase ATP-binding subunit

Gene

kdpB

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.UniRule annotationSAAS annotation

Catalytic activityi

ATP + H2O + K+(Out) = ADP + phosphate + K+(In).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3054-aspartylphosphate intermediateUniRule annotation1
Binding sitei342ATPUniRule annotation1
Binding sitei346ATPUniRule annotation1
Binding sitei391ATPUniRule annotation1
Metal bindingi514MagnesiumUniRule annotation1
Metal bindingi518MagnesiumUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processIon transport, Potassium transportUniRule annotationSAAS annotation, Transport
LigandATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding, Potassium

Enzyme and pathway databases

BioCyciCJEJ192222:GJTS-632-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase ATP-binding subunitUniRule annotation (EC:3.6.3.12UniRule annotation)
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chainUniRule annotation
Potassium-binding and translocating subunit BUniRule annotation
Potassium-translocating ATPase B chainUniRule annotation
Gene namesi
Name:kdpBUniRule annotationImported
Ordered Locus Names:Cj0677Imported
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)Imported
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 52HelicalUniRule annotationAdd BLAST19
Transmembranei64 – 83HelicalUniRule annotationAdd BLAST20
Transmembranei217 – 238HelicalUniRule annotationAdd BLAST22
Transmembranei250 – 274HelicalUniRule annotationAdd BLAST25
Transmembranei580 – 600HelicalUniRule annotationAdd BLAST21
Transmembranei612 – 631HelicalUniRule annotationAdd BLAST20
Transmembranei652 – 676HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

PTM / Processingi

Keywords - PTMi

PhosphoproteinUniRule annotation

Proteomic databases

PaxDbiQ0PAK1.

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotationSAAS annotation

Protein-protein interaction databases

IntActiQ0PAK1. 1 interactor.
STRINGi192222.Cj0677.

Structurei

3D structure databases

ProteinModelPortaliQ0PAK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108F3I. Bacteria.
COG2216. LUCA.
HOGENOMiHOG000244113.
KOiK01547.
OMAiILWLWFT.

Family and domain databases

CDDicd02078. P-type_ATPase_K. 1 hit.
Gene3Di3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_00285. KdpB. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006391. P-type_ATPase_bsu_IA.
IPR001757. P_typ_ATPase.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 1 hit.
TIGR01497. kdpB. 1 hit.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0PAK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKKQNKLIT KEILNNAIKG AFLKFDPRFM VKNPVMFMVE VGSILTLILS
60 70 80 90 100
IFPTLFNGNS DERIYNILIT FILFIILFFA NFAESIAEGR GKAQAATLRQ
110 120 130 140 150
SKKDSKARHI KSDGSEEMLN SSELKIGDIV LVKAGELIPN DGEIIEGTAS
160 170 180 190 200
VDESAITGES APVMREAGGD FSSVTGGTTV LTDFLKIKIL VGAGESFLDK
210 220 230 240 250
MINLVEGAAR QKTPNEIALN TLLIVLSLSF LMVVVSLYPF MQFLGVSLPI
260 270 280 290 300
SWLVALLVCL IPTTIGGLLS AIGIAGMDRV TRFNVIALSG KAVESCGDVD
310 320 330 340 350
TMILDKTGTI TFGNRLANEF YEVQGISKEE MIKACVLSSL KDETPEGKSI
360 370 380 390 400
VALAQKMGYE LEGNDIKEFI EFSAQNRMSG VDLQDNTKIR KGAFDAIRAY
410 420 430 440 450
ISEMNGKIPS DLETKVMEIS NLGGTPLVVC KNEKILGVIY LKDTVKPGLK
460 470 480 490 500
ERFDELRKMG IKTLMCTGDN PLTAATITKE AGLDGFIAEC KPEDKIKAIK
510 520 530 540 550
KEQAQGKIVA MTGDGTNDAP VLTQADVGIA MNSGTQAAKE AANMIDLDSN
560 570 580 590 600
PTKILEVVEI GKGLLITRGS LTTFSMTNDI AKYFAILPAM FSVVLPQMQI
610 620 630 640 650
LNIMHLATPK SAILSALIFN AIIIPLLIPI AMRGVKFKPM KSEHLLLRNL
660 670 680
SIYGLGGMIA PFIGIKIIDI PTAWILRILG V
Length:681
Mass (Da):73,748
Last modified:September 19, 2006 - v1
Checksum:i611691C96F8C7DE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA. Translation: CAL34814.1.
RefSeqiWP_002852255.1. NC_002163.1.
YP_002344096.1. NC_002163.1.

Genome annotation databases

EnsemblBacteriaiCAL34814; CAL34814; Cj0677.
GeneIDi904995.
KEGGicje:Cj0677.
PATRICifig|192222.6.peg.669.

Similar proteinsi

Entry informationi

Entry nameiQ0PAK1_CAMJE
AccessioniPrimary (citable) accession number: Q0PAK1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 19, 2006
Last sequence update: September 19, 2006
Last modified: August 30, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported