Reviewed, UniProtKB/Swiss-Prot Q0P9X8 (PEB1A_CAMJE)

Names and origin

Protein names

Recommended name:
    Major cell-binding factor
Alternative name(s):
    CBF1
    PEB1

Gene names

Name:	peb1A
Ordered Locus Names:	Cj0921c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Common antigen and a major cell adherence molecule. Most probably involved, with PEB1C, in a binding-protein-dependent transport system for an amino acid. May be involved in binding to intestinal cells.
Subcellular location	Cell surface.
Sequence similarities	Belongs to the bacterial solute-binding protein 3 family.

Ontologies

Keywords
Biological process	Transport
Domain	Signal
Technical term	3D-structure Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cell surface Inferred from electronic annotation. Source: UniProtKB-SubCell outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
fliL	Q0P8K6	1	EBI-1191594,EBI-1191158
fliY	Q0PC74	1	EBI-1191594,EBI-1191111
motB	Q0PBH3	1	EBI-1191594,EBI-1191146

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Ref.2
	Chain	27 – 259	233	Major cell-binding factor		PRO_0000031772

Sequences

	Sequence		Length	Mass (Da)
	Q0P9X8-1 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: DA132ECE87BBCBD5	FASTA	259	28,178
	10 20 30 40 50 60 MVFRKSLLKL AVFALGACVA FSNANAAEGK LESIKSKGQL IVGVKNDVPH YALLDQATGE 70 80 90 100 110 120 IKGFEVDVAK LLAKSILGDD KKIKLVAVNA KTRGPLLDNG SVDAVIATFT ITPERKRIYN 130 140 150 160 170 180 FSEPYYQDAI GLLVLKEKKY KSLADMKGAN IGVAQAATTK KAIGEAAKKI GIDVKFSEFP 190 200 210 220 230 240 DYPSIKAALD AKRVDAFSVD KSILLGYVDD KSEILPDSFE PQSYGIVTKK DDPAFAKYVD 250 DFVKEHKNEI DALAKKWGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.
[2]	"Identification, purification, and characterization of major antigenic proteins of Campylobacter jejuni." Pei Z., Ellison R.T. III, Blaser M.J. J. Biol. Chem. 266:16363-16369(1991) [PubMed: 1885571] [Abstract] Cited for: PROTEIN SEQUENCE OF 27-53.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AL111168 Genomic DNA. Translation: CAL35041.1.

PIR

A48518.

RefSeq

YP_002344319.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2V25	X-ray	1.49	A/B	1-259	[»]

ModBase

Search...

Protein-protein interaction databases

IntAct

Q0P9X8. 92 interactions.

Protein family/group databases

TCDB

3.A.1.3.16. ATP-binding cassette (ABC) superfamily.

PTM databases

PhosSite

Q0P9X8.

Genome annotation databases

GeneID

906008.

GenomeReviews

Gene locus Cj0921c in contig AL111168_GR.

KEGG

cje:Cj0921c.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

Q0P9X8.

OMA

Q0P9X8. KKSYNFS.

Family and domain databases

InterPro

IPR015683. Glutamate_receptor-rel.
IPR001638. SBP_bac_3.
IPR018313. SBP_bac_3_CS.
[Graphical view]

PANTHER

PTHR18966. Glut_Rec_Related. 1 hit.

Pfam

PF00497. SBP_bac_3. 1 hit.
[Graphical view]

SMART

SM00062. PBPb. 1 hit.
[Graphical view]

PROSITE

PS01039. SBP_BACTERIAL_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

PEB1A_CAMJE

Accession

Primary (citable) accession number: Q0P9X8
Secondary accession number(s): P45678

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	September 19, 2006
Last modified:	June 16, 2009
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)