Q0P9X8 (PEB1A_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Major cell-binding factor

Alternative name(s):
CBF1
PEB1

Gene names

Name:	peb1A
Ordered Locus Names:	Cj0921c

Organism

Campylobacter jejuni

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Common antigen and a major cell adherence molecule. Most probably involved, with PEB1C, in a binding-protein-dependent transport system for an amino acid. May be involved in binding to intestinal cells.
Subcellular location	Cell surface.
Sequence similarities	Belongs to the bacterial solute-binding protein 3 family.

Ontologies

Keywords
Biological process	Transport
Domain	Signal
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Cellular component	cell surface Inferred from electronic annotation. Source: UniProtKB-SubCell outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 26

26

Ref.2

Chain

27 – 259

233

Major cell-binding factor

PRO_0000031772

Secondary structure

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259

Helix Strand Turn

Details...

Helix

31 – 36

6

Beta strand

40 – 42

3

Beta strand

46 – 48

3

Turn

49 – 51

3

Beta strand

52 – 54

3

Helix

65 – 76

12

Beta strand

82 – 85

4

Turn

90 – 92

3

Turn

96 – 98

3

Helix

113 – 116

4

Beta strand

119 – 129

11

Beta strand

133 – 135

3

Helix

136 – 138

3

Helix

143 – 145

3

Helix

159 – 162

4

Helix

166 – 169

4

Beta strand

175 – 181

7

Helix

182 – 190

9

Beta strand

193 – 195

3

Helix

201 – 204

4

Beta strand

212 – 214

3

Beta strand

220 – 224

5

Beta strand

226 – 229

4

Helix

233 – 245

13

Helix

247 – 256

10

Sequences

	Sequence		Length	Mass (Da)
	Q0P9X8 [UniParc]. Last modified September 19, 2006. Version 1. Checksum: DA132ECE87BBCBD5	FASTA	259	28,178
	10 20 30 40 50 60 MVFRKSLLKL AVFALGACVA FSNANAAEGK LESIKSKGQL IVGVKNDVPH YALLDQATGE 70 80 90 100 110 120 IKGFEVDVAK LLAKSILGDD KKIKLVAVNA KTRGPLLDNG SVDAVIATFT ITPERKRIYN 130 140 150 160 170 180 FSEPYYQDAI GLLVLKEKKY KSLADMKGAN IGVAQAATTK KAIGEAAKKI GIDVKFSEFP 190 200 210 220 230 240 DYPSIKAALD AKRVDAFSVD KSILLGYVDD KSEILPDSFE PQSYGIVTKK DDPAFAKYVD 250 DFVKEHKNEI DALAKKWGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.
[2]	"Identification, purification, and characterization of major antigenic proteins of Campylobacter jejuni." Pei Z., Ellison R.T. III, Blaser M.J. J. Biol. Chem. 266:16363-16369(1991) [PubMed: 1885571] [Abstract] Cited for: PROTEIN SEQUENCE OF 27-53.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL111168 Genomic DNA. Translation: CAL35041.1.

PIR

A48518.

RefSeq

YP_002344319.1. NC_002163.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2V25	X-ray	1.49	A/B	1-259	[»]

ProteinModelPortal

Q0P9X8.

SMR

Q0P9X8. Positions 29-259.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q0P9X8. 92 interactions.

MINT

MINT-6484988.

Protein family/group databases

TCDB

3.A.1.3.16. ATP-binding cassette (ABC) superfamily.

PTM databases

PhosSite

Q0P9X8.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

906008.

GenomeReviews

Gene locus Cj0921c in contig AL111168_GR.

KEGG

cje:Cj0921c.

PATRIC

20058786. VBICamJej33762_0905.

Phylogenomic databases

HOGENOM

HBG698334.

OMA

VNEVIND.

ProtClustDB

PRK11917.

Enzyme and pathway databases

BioCyc

CJEJ192222:CJ0921C-MONOMER.

Family and domain databases

InterPro

IPR001638. SBP_bac_3.
IPR018313. SBP_bac_3_CS.
[Graphical view]

KO

K10039.

Pfam

PF00497. SBP_bac_3. 1 hit.
[Graphical view]

SMART

SM00062. PBPb. 1 hit.
[Graphical view]

PROSITE

PS01039. SBP_BACTERIAL_3. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

PEB1A_CAMJE

Accession

Primary (citable) accession number: Q0P9X8
Secondary accession number(s): P45678

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	September 19, 2006
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program